Thyroidectomy and the parathyroids

Michie, W.; Stowers, J. M.; Frazer, S.C.; Gunn, A.

doi:10.1002/bjs.1800520706

Cited by 35 publications

(14 citation statements)

References 38 publications

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“…As previously reported, PTH level at 4 hours after surgery was not predictive for clinical signs of hypocalcemia in this study [30]. Lastly, we believe that mean operating time was significantly longer in patients undergoing ligature of ITA terminal branches since dissection and bleeding control were more time consuming [31,32].…”

Section: Discussionmentioning

confidence: 48%

Terminal ligature of inferior thyroid artery branches during total thyroidectomy for multinodular goiter is associated with higher postoperative calcium and PTH levels

Cocchiara

Cajozzo

Amato

et al. 2010

Journal of Visceral Surgery

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Section: Discussionmentioning

confidence: 48%

Terminal ligature of inferior thyroid artery branches during total thyroidectomy for multinodular goiter is associated with higher postoperative calcium and PTH levels

Cocchiara

Cajozzo

Amato

et al. 2010

Journal of Visceral Surgery

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“…This feature was observed by Miche and colleagues as early as 1965. [2] There were 121 cases of hyperthyroidism which included 42 patients of Grave's disease and 79 patients of TNG. Hypocalcaemia was significantly associated with Grave's disease as noticed in some earlier studies.…”

Section: Discussionmentioning

confidence: 99%

“…Another study in Aberdeen Royal Infirmary noted high incidence of symptomatic patients on stress test but essentially did not correlate with serum calcium levels. [2] This feature was noted in the first 2 years following thyroidectomy.…”

Section: Introductionmentioning

confidence: 99%

Hypocalcaemia following total thyroidectomy: An analysis of 806 patients

Nair

Babu

Ramachandran

et al. 2013

Indian J Endocr Metab

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Background:Permanent hypocalcaemia following thyroidectomy causes considerable morbidity. This prospective observational study aims to define the factors likely to predict hypocalcaemia following total thyroidectomy.Materials and Methods:Patients who were subjected to total thyroidectomy during January 2005 to December 2009 were followed up for a minimum period of 1 year. Efficacy of an intraoperative parathyroid hormone assay to predict hypocalcaemia was validated.Results:Overall incidence of hypocalcaemia was 23.6% (n = 190) and that of permanent hypocalcaemia was 1.61% (n = 13). Onset was delayed up to 3rd postoperative day in 13 patients. Hypocalcaemia was significantly associated with thyroidectomy for Grave's Disease (P = 0.001), Hashimoto's thyroiditis (P = 0.003), and with incidental parathyroidectomy (P = 0.006). The intraoperative assay of parathyroid hormone showed low sensitivity (0.5) and satisfactory specificity (0.9) in predicting hypocalcemia.Conclusion:Hypocalcemia could manifest late in the immediate postoperative period and this may explain latent hypocalcemia. High incidence of hypocalcaemia noted in Grave's Disease could be due to the autoimmunity since same feature was noted associated with Hashimoto's thyroiditis and the incidence of hypocalcaemia was not high in the subgroup with toxic nodular goiter. The incidence of hypocalcemia was not affected by age or sex.

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“…In their studies they reported 24% of their cases developed Hypocalcaemia due to deficiency of Parathyroid hormone following thyroid surgery. 2 Immediate clinical manifestations of hypocalcaemia include nerve and muscle symptoms but occasionally psychotic symptoms may be observed. Persistent hypocalcaemia causes disability and a considerable financial loss due to adverse impact on health of patient.…”

Section: Introductionmentioning

confidence: 99%

Malignant Thyroid Disease; Hypocalcaemia Following Thyroid Surgery

Talpur¹

2017

TPMJ

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Thyroidectomy and the parathyroids

Cited by 35 publications

References 38 publications

Terminal ligature of inferior thyroid artery branches during total thyroidectomy for multinodular goiter is associated with higher postoperative calcium and PTH levels

Terminal ligature of inferior thyroid artery branches during total thyroidectomy for multinodular goiter is associated with higher postoperative calcium and PTH levels

Hypocalcaemia following total thyroidectomy: An analysis of 806 patients

Malignant Thyroid Disease; Hypocalcaemia Following Thyroid Surgery

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