Thyroid Nodules and Differentiated Thyroid Cancer

Bauer, Andrew J.

doi:10.1159/000363164

Cited by 17 publications

(11 citation statements)

References 223 publications

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“…Early lymphatic involvement is not rare and rare variants have been reported previously [4]. Anaplastic carcinoma of the thyroid gland is a rare form according to nomenclature of World Health Organization [5].…”

Section: Discussionmentioning

confidence: 99%

Carcinosarcoma of the Thyroid Gland

Ekici

Koçak

Bayhan

et al. 2015

Case Reports in Surgery

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Introduction. Surgeon has significant role in the management of such rare and controversial clinical entities related to thyroid gland. In this case report we have presented an elderly patient with rapid enlargement in thyroid that was related to carcinosarcoma. Case Presentation. A 60-year-old lady was presented with rapid enlargement of the thyroid gland. A fine needle aspiration of the nodule in right lobe was performed several weeks before presentation to our clinic. End diagnosis was a papillary carcinoma of the thyroid with spindle cell component. Thus the nodule was recognized to be a carcinosarcoma. Conclusion. Thyroid surgery merits a multidisciplinary approach. Indeed the surgeon should make a conclusive decision in some controversial and rare clinical entities such as carcinosarcoma.

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Section: Discussionmentioning

confidence: 99%

Carcinosarcoma of the Thyroid Gland

Ekici

Koçak

Bayhan

et al. 2015

Case Reports in Surgery

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“…Despite the majority of thyroid nodules are benign origin, about 5% to 15% account for the malignant nodules [5,6]. However, the incidence of thyroid nodules and thyroid carcinoma has increased over the last several decades [7]. Due to the similar characteristics of benign and malignant thyroid nodules and completely different treatment and prognosis, early identification of the property of the thyroid nodules is very important.…”

Section: Introductionmentioning

confidence: 99%

Acoustic Radiation Force Impulse imaging for detecting thyroid nodules: a systematic review and pooled meta-analysis.

Dong

Jiao

et al. 2015

Med Ultrason

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Aim: To investigate the diagnostic performance of shear wave velocity (SWV) using virtual touch tissue quantification (VTQ) of acoustic radiation force impulse imaging (ARFI) technology in differentiating malignant and benign thyroid nodules by conducting a meta-analysis. Material and methods: The Cochrane library, Embase, Pubmed, and Web of Science were searched for relevant studies through December 2014. Studies evaluating the diagnostic accuracy of SWV in the identification of malignant and benign thyroid nodules by using VTQ of ARFI technology were selected. The cytology or histology was used as the reference standard. The pooled sensitivity, specificity, diagnostic odds ratio, likelihood ratio, and the area under the summary receiver operating characteristic (SROC) curve were used to examine the diagnostic accuracy of SWV. Results: A total of 13 cohort studies involving 1617 thyroid nodules from 1451 patients were identified. Of 13 studies, one was a retrospective study and others were prospective studies. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio of SWV in differentiating malignant and benign thyroid nodules were 86.3% (95%CI: 78.2-91.7), 89.5% (95%CI: 83.3-93.6), 7.04 (95%CI: 4.40-11.26), 0.17 (95%CI: 0.10-0.31), and ), respectively. The area under the SROC curve was 94% (95% CI: 92-96). Conclusions: This meta-analysis indicates that VTQ is useful in evaluating the stiffness of thyroid nodules and differentiating between malignant and benign nodules. Due to the high sensitivity, specificity, and diagnostic odds ratio, SWV can be considered as a useful complement for conventional ultrasonography.

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“…Third, early identification and treatment of SPTC could potentially impact survival. Of course, most thyroid cancers are well‐differentiated with a comparatively low risk of death . The extent of management in these patients is already steeped in controversy …”

Section: Discussionmentioning

confidence: 99%

“…Of course, most thyroid cancers are welldifferentiated with a comparatively low risk of death. 16 The extent of management in these patients is already steeped in controversy. 17,18 Despite this, there are several characteristics of patients with post-HNSCC that cause them to differ from the general population with respect to potential thyroid cancers.…”

Section: Discussionmentioning

confidence: 99%