Thyroid hemiagenesis associated with the right aortic arch

Abstract

The case of a 38-year-old woman with left thyroid hemiagenesis associated with the right aortic arch is presented. The diagnosis of hemiagenesis was established by isotopic and ultrasonic imaging, and also by angiographically defined absence of the left thyroid arteries. The aortogram revealed a right aortic arch with isolation of the left subclavian artery from the aorta. Although the significance and mechanism of the concomitant development of these anomalies is unknown, this case may be the first report in the literature.

The immunohistochemical demonstration of parafollicular cells and evaluation of calcium-phosphate balance in patients with thyroid hemiagenesis

“…No thyroid arteries were seen, but a recurrent laryngeal nerve of typical localization was localized. Similarly, a lack of thyroid arteries was detected on the side of a lobe agenesis in the studies by Mariani et al as well as by Konno and Kanaya [28,30]. This might be a confirmation of a theory of developmental failure of one thyroid lobe due to disturbed vascularization.…”

“…Interestingly, among numerous cases of HT associated with different thyroid pathologies, there were no reports of medullary cancer [20,21]. In a number of patients, HT was accompanied by extrathyroidal abnormalities, including parathyroid adenoma [22], autoimmune polyglandular syndrome type III [23], Williams syndrome [24], pituitary adenoma [25], Down syndrome [26], Marfan syndrome [27], right aortic arch [28] or dysmorphic face with short stature [29]. However, it has never been investigated whether TH is associated with disturbances of the calcium-phosphate balance.…”

“…It has been hypothesized that secondarily to disturbed development of a thyroid lobe in TH, the formation of T T T T Table 1 www.fhc.viamedica.pl surrounding structures derived from the pharyngeal apparatus is aberrant, which might influence calcium, parathormon or calcitonin levels in these subjects. In some cases of HT, on the side of the agenetic lobe, no parathyroids or thyroid artery have been demonstrated [22,28,30]. On the other hand, the number and localization of parathyroid glands can vary greatly even among subjects with a normal thyroid.…”

Thyroid Hemiagenesis with Multinodular Goiter: A Case Report and Review of the Literature

“…Hyperthyroidism was reported to be the major reason for diagnosis. In general hypothyroidism was reported in a small group of patients (only in 21 cases) [9,10,13,29,[50][51][52][53]. However Mikosch et al reported a high prevalence of hypothyroidism (7 of 16 patients) in their survey in an iodine deficient geographic area [29].…”

Thyroid Hemiagenesis Presenting As Hypothyroidism – A Rare Case Report

“…Hypothyroidism remains an unusual complication of the thyroid hemiagenesis with an uncertain etiology. 10,14,15 Thyroid hormone deficiency is mainly due to peripheral and central nervous system dysfunctions that makes it even more important to diagnose hypothyroidism. 12,16 We conclude that thyroid hemiagenesis and diffuse or focal thyroid disease in the existing thyroid lobe can be demonstrated by ultrasound well and stands as investigation of choice, further associated anomalies are delineated by CT and scintigraphy helps for differentiation between hemiagenesis and suppressed thyroid lobe.…”