Thyroid Function and Physical Activity: A Population-Based Cohort Study

Dueñas, Oscar Hernando Roa; Koolhaas, Chantal M.; Voortman, Trudy; Franco, Oscar H.; Ikram, M. Arfan; Peeters, Robin P.; Chaker, Layal

doi:10.1089/thy.2020.0517

Cited by 15 publications

(14 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Indeed, Hackney and Saeidi [ 43 ] studied the effects of short-term and intense physical exercise on serum TSH and thyroid hormone concentration in young adults. On the other hand, Dueñas et al [ 44 ] failed to show significant association between thyroid function and PA, in euthyroid adults and seniors, even in the presence of both longitudinal and cross-sectional design, with a study including subjects with a wider range of age and using questionnaires. In addition, they used a validated questionnaire to estimate PA, which is well-known to be less sensitive than accelerometers [ 45 ], in participants younger than those used in its validation study.…”

Section: Discussionmentioning

confidence: 99%

Serum TSH and Daily Physical Activity in a Cohort of Nonagenarians: Results from the Mugello Study

Blasio

Dalmazi

Izzicupo

et al. 2022

JFMK

View full text Add to dashboard Cite

Background. The current literature does not furnish clear data concerning the relationship between thyroid function, sedentary time and daily physical activity (PA) in older adults with euthyroid condition. The aim of this study was to investigate the association of serum Thyrotropin-Stimulating Hormone (TSH), free Triiodothyronine (fT3) and free Thyroxine (fT4) with sedentary time and PA in a cohort of nonagenarians. Methods. A total of 108 nonagenarians (92.8 ± 3.2 years), participating in the Mugello Study, and with complete data on thyroid function, sedentary time, PA and sleeping (objectively collected through a multisensory device), were considered for the analysis. Results. Mainly, TSH negatively correlated with time spent lying down, and positively correlated with METs. fT4 levels were negatively associated with mean daily metabolic equivalents (METs) and with low-intensity PA practice (LIPAT), and positively associated with lying down and sleeping time. Similar results have been shown in the female sample. Mainly, participants with high-normal (third tertile) versus low-normal TSH (first tertile) had higher moderate-intensity PA (MIPAT) (p = 0.03). In the female sample, first TSH tertile had higher METs (p = 0.010), LIPAT (p = 0.02), MIPAT (p = 0.01) and lower time lying down (p = 0.04) than third TSH tertile. Conclusion. High-normal serum TSH and low-normal fT4 are associated with higher levels and intensity of daily PA, together with higher MIPAT continuity, in the oldest-old.

show abstract

Section: Discussionmentioning

confidence: 99%

Serum TSH and Daily Physical Activity in a Cohort of Nonagenarians: Results from the Mugello Study

Blasio

Dalmazi

Izzicupo

et al. 2022

JFMK

View full text Add to dashboard Cite

show abstract

“…Many studies have measured TSH and thyroid hormone levels after exercise in healthy individuals, but it is difficult to draw any conclusions due to inconsistencies between studies ([ 246 , 247 , 248 , 249 ]; Table 1 ). A recent study involving 2740 healthy individuals observed no changes in TSH and fT4 levels after exercise [ 250 ]. Factors contributing to inconsistencies between studies are the physical status of the subjects, the intensity, duration and type of exercise, differences in age and gender among the subjects and even the ambient temperature [ 245 ].…”

Section: Environmental Factors That Influence Tsh and Thyroid Hormone Levelsmentioning

confidence: 99%

Environmental Factors Affecting Thyroid-Stimulating Hormone and Thyroid Hormone Levels

Leko

Gunjača

Pleić

et al. 2021

IJMS

View full text Add to dashboard Cite

Thyroid hormones are necessary for the normal functioning of physiological systems. Therefore, knowledge of any factor (whether genetic, environmental or intrinsic) that alters the levels of thyroid-stimulating hormone (TSH) and thyroid hormones is crucial. Genetic factors contribute up to 65% of interindividual variations in TSH and thyroid hormone levels, but many environmental factors can also affect thyroid function. This review discusses studies that have analyzed the impact of environmental factors on TSH and thyroid hormone levels in healthy adults. We included lifestyle factors (smoking, alcohol consumption, diet and exercise) and pollutants (chemicals and heavy metals). Many inconsistencies in the results have been observed between studies, making it difficult to draw a general conclusion about how a particular environmental factor influences TSH and thyroid hormone levels. However, lifestyle factors that showed the clearest association with TSH and thyroid hormones were smoking, body mass index (BMI) and iodine (micronutrient taken from the diet). Smoking mainly led to a decrease in TSH levels and an increase in triiodothyronine (T3) and thyroxine (T4) levels, while BMI levels were positively correlated with TSH and free T3 levels. Excess iodine led to an increase in TSH levels and a decrease in thyroid hormone levels. Among the pollutants analyzed, most studies observed a decrease in thyroid hormone levels after exposure to perchlorate. Future studies should continue to analyze the impact of environmental factors on thyroid function as they could contribute to understanding the complex background of gene–environment interactions underlying the pathology of thyroid diseases.

show abstract

“…Although the method of obtaining the physical ability score in our study is different, the study is similar in that it obtained physical performance scores to observe the association with fT4. However, Dueñas et al [ 71 ] reported no association between physical activity scores and fT4 levels. We speculate that this difference in results is because these studies focused on the relationship of fT4 levels to the intensity of physical activities and exercise, while our results investigated the relationship of fT4 to changes in physical ability.…”

Section: Discussionmentioning

confidence: 99%

Effect of the Marine Exercise Retreat Program on Thyroid-Related Hormones in Middle-Aged Euthyroid Women

Byeon

Moon

Lee

et al. 2023

IJERPH

View full text Add to dashboard Cite

This study aimed to investigate the effects of a marine exercise retreat program on thyroid-related hormone levels. A total of 62 middle-aged euthyroid women participated in a 6-day marine exercise retreat program. Using thyroid-stimulating hormone (TSH) and free thyroxine (fT4) hormone levels, the participants were divided into high and low-hormone-level groups. Despite decreased TSH and fT4 levels after the program, the factors influencing changes in each group were different. TSH levels were influenced by changes in the normalized low frequency (nLF) of heart rate variability and carbon monoxide (CO) from all the participants, and changes in body fat percentage, nLF, and nitrogen dioxide (NO2) exposure level in the high TSH group. fT4 levels were influenced by changes in body mass index (BMI), NO2 exposure, and particulate matter diameter of 10 µm or less (PM10) exposure in all participants. Changes in BMI and CO exposure influenced the low fT4 group. Lastly, changes in the exercise stress test affected the high fT4 group. Thus, the marine exercise retreat program affected euthyroid thyroid-related hormone levels, and influencing factors differ depending on the initial value of the hormone.

show abstract

Thyroid Function and Physical Activity: A Population-Based Cohort Study

Cited by 15 publications

References 41 publications

Serum TSH and Daily Physical Activity in a Cohort of Nonagenarians: Results from the Mugello Study

Serum TSH and Daily Physical Activity in a Cohort of Nonagenarians: Results from the Mugello Study

Environmental Factors Affecting Thyroid-Stimulating Hormone and Thyroid Hormone Levels

Effect of the Marine Exercise Retreat Program on Thyroid-Related Hormones in Middle-Aged Euthyroid Women

Contact Info

Product

Resources

About