Thyroid Function Abnormalities among Hospital Patients of Hilly Nepal

Dangol, Raj Krishna; Lanjekar, Priya; Pulipati, Chandrashekhar

doi:10.22502/jlmc.v5i1.118

Cited by 7 publications

(18 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our result was similar to all other surveys done in different parts of the country as well as outside the country. 8,9,10,11,12 From our study, we found that the most common age group for thyroid disorders is 31 -45 (40.6%), which was similar to the data obtained in Lumbini From our study, we found that the most common type of thyroid disorder is Hypothyroidism (29.6%) followed by Subclinical hypothyroidism (28.3%), which was similar but less than that found in Shree Puspanjali Hospital Pvt. Ltd, Bharatpur-10, which was 87%9 and in Benazer Bhutto Hospital, Islamabad, which was 63%.…”

Section: Discussionsupporting

confidence: 85%

Clinical Profile of Thyroid Disorders – A retrospective study at BPKIHS

Agrawal

Rani

Maskey

2018

Jour of Diab and Endo Assoc of Nepal

View full text Add to dashboard Cite

Background: The thyroid gland produces two key metabolic hormones which regulate metabolic rate, growth and development. They play vital roles in digestion, heart and muscle function, brain development and maintenance of bones. People suffering from thyroid disorders may have autoimmune disease, ranging from primary hypothyroidism, Hashimoto’s thyroiditis, to hyperthyroidism caused by Graves’ disease. Objectives: To study clinical profile of thyroid disorders in endocrinology clinic of BPKIHS, Nepal. Methods: This is a hospital based retrospective study of past five years (2012 – 2017) done in department of internal medicine at B.P. Koirala Institute of Health Sciences, in which thyroid disorder patient records from the endocrinology clinic will be compiled together will be analyzed after classifying them according to the guidelines of the American Thyroid Association (ATA). Results: Among 584 thyroid disorder cases that were sampled, higher prevalence of thyroid disorders was seen in females, and the Male: Female ratio was 1:4.13. Most common type of thyroid disorder was Hypothyroidism (29.6%) followed by Subclinical hypothyroidism (28.3%). Conclusions: Thyroid disorders are more common in females than males and hypothyroidism being commonest thyroid disorder in our setup. Subclinical hypothyroidism is second commonest followed by hyperthyroidism. In Subclinical hypothyroidism Anti TPO antibody is most commonly found to be positive.

show abstract

Section: Discussionsupporting

confidence: 85%

Clinical Profile of Thyroid Disorders – A retrospective study at BPKIHS

Agrawal

Rani

Maskey

2018

Jour of Diab and Endo Assoc of Nepal

View full text Add to dashboard Cite

show abstract

“…Our findings also revealed that in the spectrum of thyroid disorders, subclinical hypothyroidism was reported in highest number of patient. 2,5,6,9,10 Depression, non-specific pain disorder, thyroid swelling, paresthesia and menstrual disturbances together contributed the majority of comorbidities associated with thyroid disorders. This was an important finding to guide the rational prescription of thyroid tests which would help to raise their diagnostic accuracy.…”

Section: Discussionmentioning

confidence: 99%

“…3,4 Nevertheless we have limited data to reveal burden of thyroid disorder in primary careand to suggest quality of care. [5][6][7] The aim of study is to find the burden of thyroid disorder in a rural district hospital of Nepal.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Thyroid Disorder in A Primary Care District Hospital of Nepal

Gupta¹,

Agrawal²,

Gauchan³

2019

J Nepal Med Assoc

View full text Add to dashboard Cite

Introduction: Thyroid disorders are among the common endocrine disorders and may approximate diabetes in prevalence. District hospitals are in frontline to manage chronic disorders including thyroid. Primary care workforce of physicians and mid-level providers together deliver care in these hospitals. Few hospitals are equipped with tests to diagnose thyroid disorders. The objective of the study is to find the burden of thyroid disorder in a district hospital of Nepal.Methods: This was a descriptive cross sectional study conducted in Bayalpata Hospital. One year data from July 2017 to June 2018 was collected from the electronic health record system. Data was collected from 999 patients through convenient sampling where thyroid function test was done. Subgroup analysis was done on basis of gender, symptoms at presentation and comorbidities.Results: Prevalence of thyroid disorder in a district hospital of Nepal was 171 (17.11%) at 95% confidence interval, range occurring from 14% to 20%. Among them, 130 (76%) had hypothyroidism and 41 (24%) had hyperthyroidism. Prevalence of thyroid disorder among female was 147 (14.7%) and among male was 24 (2.4%). The most common symptom was depressed mood followed by nonspecific pain disorder, thyroid swelling, paresthesia and menstrual disturbances and common comorbidities reported were depression, diabetes, hypertension, anxiety disorder and chronic gastritis. Conclusions: Our study showed the burden of thyroid disorders in a primary care district hospital with hypothyroidism being more common than hyperthyroidism. Thyroid disorder must be addressed on time to lower the burden. However, most of the rural population of Nepal lack in matters of lack of resources. So, it is suggested for the need to equip the health centers with thyroid tests and integrated workforce of physicians and mid-level providers in care delivery of thyroid disorders.

show abstract

“…In a hospital based study performed at central Nepal, out of 5230 subjects ranging from early infant to elderly age, 71% of them have euthyroidism with serum FT3 = 2.3 ± 0.6 pg/mL, FT4 = 11.5 ± 2.0 pg/mL and TSH = 2.3 ± 1.1 mIU/L [20]. In another hospital based study performed in hilly region of Nepal, 76.7% of 3136 subjects have clinically diagnosed euthyroidism [21]. In the studies of age-based variations of serum FT4 in normal thyroid subjects, its concentration trends to decrease slightly with aging having the smaller values for males than for females in younger age below 60 years [4]…”

Section: Introductionmentioning

confidence: 96%

Age- and Gender-Specific Changes in Thyroid Size and Thyroid Function Test Values of Euthyroid Subjects

Lamichhane¹,

Pant²,

Lamichhane³

et al. 2018

JBM

View full text Add to dashboard Cite

Background: The thyroid status is evaluated by two clinical diagnostic tests which are thyroid ultrasonography and thyroid function tests. The objective of this research is to critically analyze the age and gender based variations of thyroid volume and thyroid hormone levels in the hospital based euthyroid subjects. Methodology: A total of 221 euthyroid subjects aged 1-86 years were selected to observe the normal thyroid size by ultrasonography at Department of Radiology and the thyroid function test values (FT3, FT4 and TSH) of 2413 euthyroid subjects aged (<1)-93 years were observed at Department of Biochemistry, Tribhuvan University Teaching Hospital, Kathmandu, Nepal during January 2017 to February 2018. The observed data were analyzed graphically and statistically to check the cross-correlations among the variables. Results: The best fitted equations with significant correlation coefficients and p < 0.05 provide the empirical relations between any two of the observed variables: age, thyroid lobe volumes, FT3, FT4 and TSH. The mean ± SD (p < 0.0001) of thyroid volume, FT3, FT4 and TSH are 4.74 ± 2.30 mL, 5.46 ± 0.82 pmol/L, 14.09 ± 2.71 pmol/L and 2.30 ± 0.98 mIU/L, respectively. Conclusion: The thyroid size first increases and then decreases whereas the thyroxin level first decreases and then increases with aging. Left lobe volume is almost same for both genders and right lobe volume is higher in males. The thyroid size in menarche and menopause periods of females is larger than that of males. Such age-and gender-specific changes recommend the new reference ranges for the normal thyroid functions.

show abstract

Thyroid Function Abnormalities among Hospital Patients of Hilly Nepal

Cited by 7 publications

References 13 publications

Clinical Profile of Thyroid Disorders – A retrospective study at BPKIHS

Clinical Profile of Thyroid Disorders – A retrospective study at BPKIHS

Prevalence of Thyroid Disorder in A Primary Care District Hospital of Nepal

Age- and Gender-Specific Changes in Thyroid Size and Thyroid Function Test Values of Euthyroid Subjects

Contact Info

Product

Resources

About