Thymochinon – das Gelbe vom Öl

Spiller, Sandro; Mettke, Peter; Siehl, Hans‐Ullrich; Zeller, Klaus‐Peter; Sicker, Dieter; Berger, Stefan

doi:10.1002/ciuz.201400660

Cited by 3 publications

(1 citation statement)

References 14 publications

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“…The column (XSelect CSH C18, 3 mm × 150 mm, 3.5 µm with a guard column of the same material, 2.1 mm × 5 mm; Waters, Eschborn, Germany) was maintained at 40 • C. The resulting backpressure was approximately 220 bars. Chromatograms were recorded at 254 nm, i.e., the maximum of the TQ UV spectrum [12,13]. Data were recorded for 10 min after each injection, and peaks were integrated using the software PeakSimple (version 4.51, SRI Inc., Bad Honnef, Germany) via a PeakSimple Interface Box 202 (Schambeck SFD GmbH, Bad Honnef, Germany).…”

Section: Hplc Analysismentioning

confidence: 99%

Screening of Thymoquinone Content in Commercial Nigella sativa Products to Identify a Promising and Safe Study Medication

et al. 2022

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(1) Background: Thymoquinone (TQ) is the leading compound accounting for the pharmacological effects of Nigella sativa seed oil, also known as black seed oil. This study aimed to analyze the TQ content of commercial black seed oils and black seed oil-containing capsules to obtain information on the quality of the products and to find a promising and safe study medication for a putative clinical study. (2) Methods: Six black seed oils and five black seed oil-containing capsules were analyzed. TQ was quantified using a validated method consisting of a simple methanolic extraction and a fast HPLC-UV analysis. (3) Results: The TQ content varied from 3.08 to 809.4 mg/100 g (mean). The highest TQ content was found in a bottled oil, which might be considered for a clinical study. A dose of 4 mL of this oil per day contains 30 mg TQ, which is unlikely to be harmful. Based on the literature, a safe daily TQ dosage appears to be <48.6 mg per adult. (4) Conclusions: These findings suggest that black seed products should be regulated regarding TQ content to enable consumers to buy black seed food supplements of known content for the maintenance and improvement of health.

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Section: Hplc Analysismentioning

confidence: 99%

Screening of Thymoquinone Content in Commercial Nigella sativa Products to Identify a Promising and Safe Study Medication

et al. 2022

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2019

Natural Products

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Die enantiomeren Carvone von Krause Minze und Kümmel

Titus¹,

Siehl²,

Zeller³

et al. 2017

Chemie in nserer Zeit

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Jedem von uns ist auch bekannt, dass bestimmte Kaugummi-Sorten nach Krause Minze schmecken, wie WRIGLEY'S SPEARMINT CHEWING GUM. Auch Zahnpasta kann Krause-Minze-Öl enthalten.Einer Sage nach ist Griechenland der Ursprungsort der Gattung Minze, die dort "schon immer" genutzt wird. Dort soll sie auch zu ihrem Namen gekommen sein. Minthe war eine wunderschöne Wassernymphe, die unsterblich in Hades, den griechischen Gott der Unterwelt verliebt war. Als eines Tages Phersephone, die Frau des Hades, an dem Fluss Acheron entlang lief, begegnete sie ihrem Mann und dessen Geliebter Minthe. Wütend wie sie war, nahm sie Rache, indem sie Minthe in eine krautige, kleine Pflanze mit unauffälligen Blättern verwandelte, auf die leicht getreten werden kann. Hades dagegen zeigte Mitleid für Minthe und versuchte sie zu trösten. Er stattete sie mit einem göttlichen, aromatischen Duft aus, der für immer anhielt. Aus: www.greek-gods.info/greek-gods/hades/myths/pluto-andmenthe/(August 2016)

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Thymochinon – das Gelbe vom Öl

Cited by 3 publications

References 14 publications

Screening of Thymoquinone Content in Commercial Nigella sativa Products to Identify a Promising and Safe Study Medication

Screening of Thymoquinone Content in Commercial Nigella sativa Products to Identify a Promising and Safe Study Medication

Coloured Compounds

Die enantiomeren Carvone von Krause Minze und Kümmel

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