“…In 13 critically ill patients treated by intravenous infusion of chloroform‐activated bovine fibrinolysin combined with anticoagulant therapy, five died and the remaining eight showed some degree of clinical improvement (Herdorn et al 1960). In an angiographically controlled study of seven patients with carotid or cerebral occlusion treated with thrombolytic enzymes evidence of complete vascular clearing was obtained in five, and two showed partial clearing (Sussman and Fitch 1961).…”