Three novel spiral chain Nd (III) Eu (III) Sm (III)complexes bridged by 1,1 '(1,4‐phenylene‐bis [methylene])‐bis (pyridine‐3‐carboxylicaicd): Synthesis, structural characterization, and antitumor activity

Abstract

In this work, three new complexes [Ln2(L)3·H2O]n (where Ln = Nd(1)、Eu (2) and Sm (3)) have been synthesized by H2L (H2L = 1,1 ‘(1,4‐phenylene‐ bis [methylene])‐bis (pyridine‐3‐carboxylicaicd)) and were characterized by X‐ray single crystal diffraction and PXRD. The interaction of these complexes with FS DNA (fish sperm DNA) and the DNA binding constants of the complexes were determined using UV spectroscopy, indicating their ability to bind to FS DNA. The DNA binding constants k of the three complexes were 1.0186 × 104, 5.047 × 103, and 5.115 × 103, respectively. The results of UV spectrum showed that the complex 1–3 was bound to DNA through hydrogen bonding. The interaction of the complexes with FS DNA was studied by fluorescence spectroscopy. The stern‐volmer quenching values of complexes 1, 2, and 3 were 0.186, 0.093, and 0.114, respectively. Electrophoresis experiments showed that the three complexes could cleave DNA molecules. In addition, flow cytometry, and morphological apoptosis studies showed that the complex could induce apoptosis of HeLa tumor cells. Results all the three complexes had potential medicinal value.

Two Copper-Containing Polyoxometalate-Based Metal–Organic Complexes as Heterogeneous Catalysts for the C–H Bond Oxidation of Benzylic Compounds and Olefin Epoxidation

“…Besides, excellent flexibility enables it to rotate and bend freely in the assembly process, thus meeting the requirements of coordination. Apart from that, the ligand shows symmetry to some degree, which improves the stability of synthesized complexes. , It thus provides an ideal option for the construction of copper-containing POM-based MOCs. Taking these into account, copper nitrate was handpicked as the reactant and assembled with classical Keggin-type polyanions in the presence of H 2 pbba to prepare novel POM-based MOCs catalysts for monooxygenation oxidation reactions.…”