Three New Spectrophotometric Methods for Simultaneous Determination of Hydrochlorothiazide and Amiloride Hydrochloride in Sugar-Coated Tablets

Electrochemical behavior and determination of amiloride drug in bulk form and pharmaceutical formulation at mercury electrodes

“…The drug has been determined in pharmaceutical preparations and biological fluids using several methods including, spectrophotometry [2][3][4][5][6][7][8][9][10], high performance liquid chromatography [5,11,12], fluorimetry [13][14][15], capillary isotachophoresis [16], chemiluminescence oxidation [17] and differentialpulse polarography [18]. No adsorptive stripping voltammetric procedures have been reported to date for the determination of amiloride.…”

Spectrophotometric and Chemometric Methods for Simultaneous Determination of Two Anti-Hypertensive Drugs in their Combined Dosage Form

“…Spectroscopic [8][9][10], High Performance Liquid Chromatography (HPLC) [11][12][13], Thin Layer Chromatography (TLC) [14], Electrochemical [15][16][17] and mass spectrometry [18] methods for estimation of MOX alone or in combination with other drugs in pharmaceutical preparation have been reported. Hydrochlorothiazide alone or in combination with other drugs is estimated by HPLC [19][20][21][22][23][24][25][26][27][28][29], TLC-densitometry [30][31][32][33][34][35][36], capillary electrophoresis [37][38][39], electrochemical [40][41][42][43] and spectroscopic methods [44][45][46][47][48][49][50][51][52][53]. Simultaneous estimation of MOX and HCT has been reported by RP-HPLC [54,…”

Estimation of Irbesartan in Bulk and Dosage Forms by New Simple UV Spectrophotometry Using Hydrotropic Technique

“…Irbesartan, a non peptide tetrazole derivative, has anti hypertensive property [1]. It is an angiotensin II antagonist that selectively blocks the binding of an angiotensin II to the angiotensin I receptor [2]. The chemical structure of Irbesartan is shown ( Figure 1).…”