Three Interferometric Methods for Measuring the Thickness of Layers of the Tear Film

King‐Smith, P. Ewen; Ba, Fink; Fogt, Nick

doi:10.1097/00006324-199901000-00025

Cited by 90 publications

(60 citation statements)

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“…This difficulty in interpreting LLPs (especially the thinner patterns) and the lack of a huge bank of LLP images for reference purposes has meant that many eye care professionals abandoned this test. Other devices for objectively evaluating lipid layer patterns have been designed, from a sophisticated optical system mounted in the laboratory [15] to a digital DR-1 camera designed to evaluate lipid layer thickness [16]. The main drawback of Tearscope compared to the DR-1 camera is that its LLP images show an iris background.…”

Section: Discussionmentioning

confidence: 99%

“…These drawbacks have led to decrease in the use of this useful technique among clinicians and even withdrawal of the Tearscope from the market. This has led to the development of techniques designed to objectively calculate lipid layer thickness using a sophisticated optic system [15]. Other techniques use an interference camera to assess lipid layer thickness by only analysing interference colours [16].…”

Section: Introductionmentioning

confidence: 99%

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Interobserver and intraobserver repeatability of lipid layer pattern evaluation by two experienced observers

García-Resúa¹,

Pena-Verdeal²,

Miñones³

et al. 2014

Contact Lens and Anterior Eye

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Interobserver and intraobserver repeatability of lipid layer pattern evaluation by two experienced observers

García-Resúa¹,

Pena-Verdeal²,

Miñones³

et al. 2014

Contact Lens and Anterior Eye

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“…It is also noticeable that the reflectance curve contrast is generally higher at longer wavelengths, which may attribute to the film thickness uniformity within the measurement spot, since shorter wavelengths are more sensitive to the local film uniformity variation. 27 Starting from the initial film thickness just after a drop of the AT is applied to the time when film thickness is not measurable, Fig. 4 shows the AT film thinning dynamics of the horizontally positioned model eye with and without contact lenses (Bausch& Lomb SofLens, Cooper Vision AVAIRA, and Bausch&Lomb PureVision).…”

Section: Measurements Of At Film On a Model Eye With And Without A Comentioning

confidence: 99%

Tear film measurement by optical reflectometry technique

Wang

et al. 2014

J. Biomed. Opt

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Abstract. Evaluation of tear film is performed by an optical reflectometer system with alignment guided by a galvanometer scanner. The reflectometer system utilizes optical fibers to deliver illumination light to the tear film and collect the film reflectance as a function of wavelength. Film thickness is determined by best fitting the reflectance-wavelength curve. The spectral reflectance acquisition time is 15 ms, fast enough for detecting film thickness changes. Fast beam alignment of 1 s is achieved by the galvanometer scanner. The reflectometer was first used to evaluate artificial tear film on a model eye with and without a contact lens. The film thickness and thinning rate have been successfully quantified with the minimum measured thickness of about 0.3 μm. Tear films in human eyes, with and without a contact lens, have also been evaluated. A high-contrast spectral reflectance signal from the precontact lens tear film is clearly observed, and the thinning dynamics have been easily recorded from 3.69 to 1.31 μm with lipid layer thickness variation in the range of 41 to 67 nm. The accuracy of the measurement is better than AE0.58% of the film thickness at an estimated tear film refractive index error of AE0.001. The fiber-based reflectometer system is compact and easy to handle.

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“…9 This has led to the development of techniques designed to objectively calculate lipid layer thickness using a sophisticated optical system. 10 Other techniques use an interference camera to assess lipid layer thickness by only analyzing interference colors. 11 This study was designed to validate a new method of classifying the lipid layer of the tear film based on assessing both texture and color patterns.…”

mentioning

confidence: 99%