Three-dimensional ultrasound evaluation of the placenta

Hata, Toshiyuki; Tanaka, Hirokazu; Noguchi, Junko; Hata, Kohkichi

doi:10.1016/j.placenta.2010.11.001

Cited by 99 publications

(104 citation statements)

References 68 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The thick, heterogeneous (jellylike) appearance of the placenta is also associated with perinatal death, hypertensive diseases, fetal growth restriction and preterm delivery [23]. Three-dimensional Power Doppler analysis in fetal growth restricted pregnancies have evidenced that decreased placental vascularity and impaired budding of the villous circulation contribute to the thick and heterogeneous (jellylike) placenta [24].…”

Section: Discussionmentioning

confidence: 99%

Acoustic radiation force impulse elastosonography of placenta in maternal red blood cell alloimmunization: a preliminary and descriptive study

Çetin¹,

Karaman²,

Arslan

et al. 2017

Med Ultrason

View full text Add to dashboard Cite

Aims: Maternal red blood cell alloimmunization is an important cause of fetal morbidity and mortality in the perinatal period, despite well-organized prophylaxis programs. The objective of the study was to evaluate placental elasticity by using Acoustic Radiation Force Impulse (ARFI) in Rhesus (Rh) alloimmunized pregnant women with hydropic and nonhydropic fetuses and to compare those with healthy pregnant women. Material and methods: This case-control and descriptive study comprised twenty-eight healthy pregnant women, 14 Rh alloimmunized pregnant women with nonhydropic fetuses, and 16 Rh alloimmunized pregnant women with hydropic fetuses in the third trimester of pregnancy. Placental elasticity measurements were performed by ARFI elastosonography at the day of delivery. The maternal characteristics and neonatal outcomes of the patients were also noted. Results: The highest mean placental ARFI scores were observed in Rh alloimmunized pregnant women with hydropic fetuses (1.13 m/s) (p=0.001). Healthy controls and Rh alloimmunized pregnant women with nonhydropic fetuses had similar mean placenta ARFI scores (0.84 m/s, 0.88 m/s, respectively) (p<0.05). Conclusions: Based on the present findings, the placenta becomes stiffer in Rh alloimmunized pregnancies complicated with hydrops fetalis. The increased placental ARFI scores may be a supplemental marker for adverse pregnancy outcomes, additional to Doppler evaluation of middle cerebral artery. This data should be confirmed with a large sample size and prospective studies by using serial measurements of ARFI elastosonography in maternal red blood cell alloimmunization.

show abstract

Section: Discussionmentioning

confidence: 99%

Acoustic radiation force impulse elastosonography of placenta in maternal red blood cell alloimmunization: a preliminary and descriptive study

Çetin¹,

Karaman²,

Arslan

et al. 2017

Med Ultrason

View full text Add to dashboard Cite

show abstract

“…Dengan kemajuan terbaru dalam 3D USG daya Doppler, evaluasi yang lebih kuat dari vaskularisasi dan aliran darah plasenta dapat dilakukan. 25 Penelitian yang dilakukan Odeh 26 menyatakan, 3D Power Doppler dari plasenta pada trimester pertama bisa memprediksi masalah pada kehamilan tetapi tidak dapat mendeteksi perbedaan indeks aliran darah pada wanita yang mengalami PE dan volume plasenta tidak sesuai untuk memprediksi PE pada tahap awal. Blood Pressure and Mean Arterial Pressure (MAP) Perubahan kecil dalam tekanan darah adalah penanda risiko berkembangnya PE.…”

Section: -24unclassified

PlGF/sFlt‑1 as Early Detection Biomarker for Preeclampsia

Sinuraya¹,

Nisa

Lokajaya

et al. 2017

Indones J Clin Pharm

View full text Add to dashboard Cite

AbstrakProgram Millenium Development Goals (MDGs) yang dilakukan sejak tahun 2003 belum berhasil mencapai tujuannya, termasuk untuk meningkatkan kesehatan ibu dengan target menurunkan Angka Kematian Ibu (AKI) sebesar tiga perempatnya antara tahun 1990 sampai 2015. Program ini kemudian dilanjutkan menjadi Sustainable Development Goals (SDGs) dengan salah satu fokusnya yaitu menurunkan AKI hingga di bawah 70 per 100.000 kelahiran hidup serta mengurangi sepertiga kematian bayi prematur akibat penyakit tidak menular. Angka kematian ibu di Indonesia cukup tinggi apabila dibandingkan dengan negara-negara lainnya di wilayah Asia Tenggara. Pada umumnya penyebab utama kematian ibu adalah pendarahan (28%), preeklampsia (PE)/eklampsia (24%), infeksi (11%), komplikasi persalinan (5%) dan abortus (5%). Preeklampsia (PE) merupakan penyakit hipertensi yang disertai dengan proteinuria yang terjadi pada saat usia kehamilan mencapai 20 minggu (trimester kedua). Penyakit ini umumnya tidak terdiagnosis namun terlihat setelah berdampak pada gangguan ibu dan janin dan apabila tidak ditangani dengan segera, maka dapat menyebabkan kematian bagi ibu pada proses persalinan. Dilaporkan bahwa rata-rata insiden kejadia PE di seluruh dunia adalah 2-10%. Berbagai upaya terus dilakukan untuk menurunkan angka kematian Ibu ini, salah satunya adalah dengan pencarian metode deteksi dini. Tujuan penulisan review ini adalah untuk mengkaji metode deteksi dini apa yang paling efektif dan efisien untuk mengatasi PE. Metode dalam review ini adalah penelusuran data berbasis Pubmed, Scopus dan Google Scholar dan tanpa pembatasan index factor dengan menggunakan kata kunci "biomarker, preeclampsia", "early detection, preeclampsia". Hasil review menunjukkan bahwa biomarker placental growth gactor (PlGF) dan soluble Fms-like tyrosine kinase 1 (sFlt-1) merupakan biomarker spesifik dengan sensitivitas dan spesifisitas yang tinggi dalam pendeteksian PE. Kata kunci:Biomarker PlGF/sFlt-1, deteksi dini, preeklampsia PlGF/sFlt-1 as Early Detection Biomarker for Preeclampsia AbstractMillennium Development Goals (MDGs) had been conducted since 2003 with uncomplished outcome target, particularly improving maternal health and lowering maternal mortality until one-fourth of population from 1990 until 2015. Then, this program was continued through Sustainable Development Goals (SDGs) in 2015 with lowering maternal mortality below 70 per 100,000 live births and reducing premature mortality due to one-third because of uncommunicable diseases. Maternal mortality in Indonesia is quite high compared with the other countries in the Southeast Asia. Generally, the main causes of maternal death are haemorrhage (28%), preeclampsia (PE)/eclampsia (24%), infection (11%), complications from birth delivery (5%), and unsafe abortion (5%). Preeclampsia (PE) is a hypertension disease accompanied with proteinuria that occuring in 20 weeks of pregnancy (second trimester). The disease is commonly unvisible and underdiagnosed until clinical manifestations were presented (e.g. maternal and fet...

show abstract

“…This was subsequently repeated in normal, full-term placentas by Rhodin and Terzakis (7), while Leiser and co-workers (8) later carried out 3D reconstructions of the peripheral stem villous tree based on serial semi-thin sections which were photographed, magnified and converted to drawings. More recently, representation of the vascular architecture 5 has been achieved by corrosion casts (9), micro-computed tomography (10), 3D power Doppler ultrasound (11) and confocal microscopy (12).…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional digital reconstruction of human placental villus architecture in normal and complicated pregnancies

McCarthy

Orsi

Treanor

et al. 2016

European Journal of Obstetrics & Gynecology and Reproductiv

View full text Add to dashboard Cite

ObjectiveThis study aimed to examine the use of digital technology in the three-dimensional reconstruction of human placentas. Study DesignPlacentas obtained at term elective caesarean section were sampled, formalin-fixed and embedded in paraffin. Two hundred 5 µm consecutive sections were cut from each specimen and the resultant slides stained with haematoxylin and eosin. Slides were then scanned and the digitised images reconstructed using customised software. ResultsThree-dimensional reconstructions were successfully achieved in placentas from normal pregnancies and those complicated by pre-eclampsia, growth restriction, and gestational diabetes. Marked morphological differences were readily identifiable, most clearly in the stem villus architecture. ConclusionThis method is an emerging research tool for examining placental histoarchitecture at high resolution and gaining clinically relevant insight into the placental pathology allied to pregnancy complications such as PET, IUGR and GD.

show abstract

Three-dimensional ultrasound evaluation of the placenta

Cited by 99 publications

References 68 publications

Acoustic radiation force impulse elastosonography of placenta in maternal red blood cell alloimmunization: a preliminary and descriptive study

Acoustic radiation force impulse elastosonography of placenta in maternal red blood cell alloimmunization: a preliminary and descriptive study

PlGF/sFlt‑1 as Early Detection Biomarker for Preeclampsia

Three-dimensional digital reconstruction of human placental villus architecture in normal and complicated pregnancies

Contact Info

Product

Resources

About