Three‐dimensional surface imaging for clinical trials: Improved precision and reproducibility in circumference measurements of thighs and abdomens

Weiss, Elliot; Barzilai, Ori; Brightman, Lori; Chapas, Anne; Hale, Elizabeth K.; Karen, Julie; Bernstein, Leonard; Geronemus, Roy G.

doi:10.1002/lsm.20863

Cited by 15 publications

(13 citation statements)

References 15 publications

(14 reference statements)

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“…In this study, this was minimized by having two independent evaluators and four repetitive measures of each area for statistical analysis. Our data confirms the feasibility, reliability and reproducibility of quantitative volume measurements using three‐dimensional imaging as demonstrated before . The quantification of volume change in the control site, which was not statistically significant, also supports the conclusion that the change of average weight during the study (average of 2 lb loss over 2 months) cannot account for the calculated loss of volume in the treated side.…”

Section: Discussionsupporting

confidence: 88%

“…In addition, as reported before the 3D imaging analysis was able to detect subtle changes in volume loss ( Fig. 6) and proved to be more superior than use of blinded evaluators to detect effectiveness of treatment [12].…”

Section: Discussionsupporting

confidence: 65%

“…This was the first study to quantify volume after fat grafting and to show that threedimensional imaging can reliably be used to analyze volume changes even in single digit range [11]. The validation of the use of 3D imaging as a precise and reproducible tool for measurement of body circumference has also been demonstrated before [12]. In this study Weiss et al [12] demonstrated the feasibility of using 3D imaging in clinical trials to reliably detected minute quantitative changes in body shape.…”

Section: Discussionmentioning

confidence: 84%

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Three‐dimensional volumetric quantification of fat loss following cryolipolysis

et al. 2013

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Background and Objectives Cryolipolysis is a noninvasive and well-tolerated treatment for reduction of localized subcutaneous fat. Although several studies demonstrate the safety and efficacy of this procedure, volumetric fat reduction from this treatment has not been quantified. This prospective study investigated the change in volume of fat after cryolipolysis treatment using three-dimensional (3D) photography. Materials and Methods A prospective study of subjects treated with cryolipolysis on the flank (love handle) was performed at Massachusetts General Hospital. Volume measurements were performed with a Canfield Scientific Vectra three-dimensional camera and software to evaluate the amount of post procedure volume change. Clinical outcomes were assessed with caliper measurements, subject surveys, and blinded physician assessment of photographs. Results Eleven subjects were enrolled in this study. Each subject underwent a single cycle of cryolipolysis to one flank. The untreated flank served as an internal control. The follow up time after treatment was two months. The mean amount of calculated absolute fat volume loss using 3D photography from baseline to 2 months follow up visit was 56.2 ± 25.6 from the treatment site and 16.6 ± 17.6 cc from the control (p < 0.0001). A mean absolute difference of 39.6 cc between the treated and untreated sides was calculated at 2 months post-treatment. Comparison of caliper measurements from baseline to 2 months post-treatment demonstrated significant reduction of the treated flank from 45.6 ± 5.8 mm at baseline to 38.6 ±4.6 mm at 2 months post-treatment (p<0.001). The untreated flank did not show significant reduction with caliper measurements demonstrating 45.3 ± 5.0 mm at baseline and 44.6 ± 5.1 mm at 2 months post-treatment (p=0.360). No unexpected side effects or adverse events were reported. Post-treatment satisfaction surveys demonstrated 82% of subjects were satisfied with the results. Conclusions Cryolipolysis is a safe, well-tolerated and effective noninvasive fat removal methodology that on average leads to 39.6 cc of fat loss at 2 months after a single treatment cycle.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 65%

Section: Discussionmentioning

confidence: 84%

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Three‐dimensional volumetric quantification of fat loss following cryolipolysis

et al. 2013

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“…Entre las ventajas mencionadas, asociadas al depósito térmico de los 2 láseres, se suman los efectos notables en la retracción de la piel según los resultados de este estudio y de acuerdo también con otros autores (3). La cámara digital de superficie constituye un método de diagnóstico comparativo fiable y objetivo de evaluación de la textura-flacidez cutánea (14,15). Weiss en 2009 (16), y nosotros mismos en 2012 y 2014 (7,17), hemos comunicado sobre los buenos resultados alcanzados por la lipólisis láser para la remodelación de rodillas y pantorrillas, observando una alta satisfacción por parte de las pacientes tratadas.…”

Section: Discussionunclassified

Criterios en la selección de pacientes para optimizar resultados en liposucción asistida por láser de abdomen y flancos: análisis de 340 cirugías

Moreno-Moraga

Alcolea²,

Torre³

et al. 2014

Cir. plást. iberolatinoam.

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“…The calibrated dimensional imaging system collected each image in under 4 ms to produce a 3D model. Vectra systems have been validated for accuracy and are in clinical use . Digital 2D images were obtained using a Phase One P25 Camera Back, Hasselblad 503w Camera System, 2kWatt Studio Flash System (Canfield Scientific, Inc.).…”

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confidence: 99%