Three-dimensional paper-based electrochemiluminescence device for simultaneous detection of Pb2+ and Hg2+ based on potential-control technique

Zhang, Meng; Ge, Lei; Ge, Shenguang; Yan, Mei; Yu, Jinghua; Huang, Jiadong

doi:10.1016/j.bios.2012.09.022

Cited by 175 publications

(46 citation statements)

References 38 publications

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“…This method presents a wide range of applications including biochemical analysis, health diagnostics, food quality control, environmental monitoring and forensic analysis [5][6][7][8]. Colorimetric [9][10][11][12][13][14][15][16], electrochemical [17][18][19], chemiluminescence [20,21], electrochemiluminescence [22], and electrical conductivity [23] detections are main quantifying approaches in the lab-on-paper method although other techniques such as mass spectrometry [24] and surface enhanced Raman spectroscopy [25] have also been applied. Among these methods, colorimetric detection is the most useful method because of its simplicity and easy performance by applying inexpensive and non-sophisticated image analysis software such as Photoshop and also instruments such as a digital camera, scanner or even a mobile phone camera [14,15].…”

Section: Introductionmentioning

confidence: 99%

Application of curcumin nanoparticles in a lab-on-paper device as a simple and green pH probe

Pourreza

Golmohammadi

2015

Talanta

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Section: Introductionmentioning

confidence: 99%

Application of curcumin nanoparticles in a lab-on-paper device as a simple and green pH probe

Pourreza

Golmohammadi

2015

Talanta

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“…Yu's group has fabricated a 3D microfluidic device that simultaneously detected two species, Pb 2 + and Hg 2 + . [51] The 3D nature of the device allowed for the two metal ions to be simultaneously present in the detection zone but individually quantitated. In this device, wax hydrophobic barriers defining the electrochemical cell were patterned onto 2 pieces of 20.0 mm 20.0 mm paper (paper-A and paper-B, with circular zones of 4 mm and 8 mm diameters, respectively).…”

Section: D Origami Microfluidic Devicesmentioning

confidence: 99%

Electrochemiluminescence Detection in Paper‐Based and Other Inexpensive Microfluidic Devices

et al. 2017

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There is a need in the field of microfluidics for integration of analytical detection methods onto small fluidic chips. Electrogenerated chemiluminescence (ECL) is an effective method for detecting a wide range of analytes, including small molecules, metal ions and bacteria. This Minireview discusses recent applications of ECL-based detection methods to inexpensive microfluidic devices. We discuss various paper and cloth based devices, including 3D-origami devices and devices utilizing bipolar electrodes. We also discuss novel devices that have replaced traditional instrumentation with inexpensive and portable equipment, such as mobile phones.

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“…The data was analysed based on the red pixel intensity of the ECL emission, which was correlated with a calibration curve, hence the analyte concentration. Other applications to date included sensing tumour markers [103,124,126] and ions [128].…”

Section: Electrochemiluminescence (Ecl)mentioning

confidence: 99%

Point-of-Care Diagnostics

Yetisen

2014

Holographic Sensors

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Rapid tests that are low-cost and portable are the first line of defence in healthcare systems. Dipstick and lateral-flow are the two universal assay formats as they are lightweight and compact, and provide qualitative results without external instrumentation. However, existing formats have limitations in the quantification of analyte concentrations. Hence, the demand for sample preparation, improved sensitivity and user-interface has challenged the commercial products. Recently, capabilities, sensors and readout devices were expanded to multiplexable assays platforms, which might transcend the capabilities of existing design format of diagnostic tests. This chapter outlines the evolution of diagnostic devices and current trends in the development of qualitative and quantitative sensing devices for applications in healthcare, veterinary medicine, environmental monitoring and food safety. The chapter also discusses design parameters for diagnostics, their functionalisation to increase the capabilities and the performance, emerging sensing platforms and readout technologies. The factors which limit the emerging rapid diagnostics to become commercial products are also discussed.The life expectancy has grown worldwide, which also increased the healthcare spending [1, 2]. For example, 720 million people will be aged 65 or older by 2020. Currently four in five people over the age of 75 take at least one prescribed medicine, and this trend is set to increase [3]. For some of the medications, large pharma find it the hard to recover R&D costs while the pressure from the regulatory agencies also increased for the use of new drugs as the first line of defence based on efficacy and cost. Hence, the global healthcare trends and ever increasing pressure from regulatory agencies put a strong case for the development of diagnostics for healthcare monitoring as well as the evaluation of drug efficacies in clinical trials. All these considerations parallels governments' and insurance companies' interests in obtaining the best performance possible and treatment benefits they support. These trends are behind the driving force for the development of diagnostics that can reduce the healthcare costs by developing effective drugs and identifying diseases and conditions at an early stage.The major stumbling block in monitoring and controlling diseases/contaminations remains delivering simple, low-cost and robust diagnostic tests [4,5]. In the developing world, the basic healthcare infrastructure and trained healthcare personnel are

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Three-dimensional paper-based electrochemiluminescence device for simultaneous detection of Pb2+ and Hg2+ based on potential-control technique

Cited by 175 publications

References 38 publications

Application of curcumin nanoparticles in a lab-on-paper device as a simple and green pH probe

Application of curcumin nanoparticles in a lab-on-paper device as a simple and green pH probe

Electrochemiluminescence Detection in Paper‐Based and Other Inexpensive Microfluidic Devices

Point-of-Care Diagnostics

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