Three-dimensional MR Neurography of the Brachial Plexus: Vascular Suppression with                     Low-dose Ferumoxytol

Pedrick, Emily G; Sneag, Darryl B.; Colucci, Philip G.; Duong, MyLinh T.; Tan, Ek Tsoon

doi:10.1148/radiol.221087

Cited by 3 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For instance, FE-MRA is capable of depicting deep venous thrombosis of the lower extremities, and is able to illustrate the extent of the thrombus even in the case of slow flow [ 13 ]. Furthermore, the suppression of minor venous blood signals through black-blood imaging can enhance nerve visualization, leading to increased diagnostic confidence [ 14 ] (Fig. 2 ).…”

Section: Ferumoxytol’s Characteristics In Mrimentioning

confidence: 99%

See 1 more Smart Citation

Unveiling the next generation of MRI contrast agents: current insights and perspectives on ferumoxytol-enhanced MRI

Si,

Du,

Tang

et al. 2024

National Science Review

View full text Add to dashboard Cite

Contrast-enhanced magnetic resonance imaging (CE-MRI) is a pivotal tool for global disease diagnosis and management. Since its clinical availability in 2009, the off-label use of ferumoxytol for ferumoxytol-enhanced MRI (FE-MRI) has significantly reshaped CE-MRI practices. Unlike MRI that's enhanced by gadolinium-based contrast agents, FE-MRI offers advantages such as reduced contrast agent dosage, extended imaging windows, no nephrotoxicity, higher MRI time efficiency, and the capability for molecular imaging. As a leading superparamagnetic iron oxide contrast agent, ferumoxytol is heralded as the next generation of contrast agents. This review delineates the pivotal clinical applications and inherent technical superiority of FE-MRI, providing an avant-garde medical-engineering interdisciplinary lens, thus bridging the gap between clinical demands and engineering innovations. Concurrently, we spotlight the emerging imaging themes and new technical breakthroughs. Lastly, we share our own insights on the potential trajectory of FE-MRI, shedding light on its future within the medical imaging realm.

show abstract

Section: Ferumoxytol’s Characteristics In Mrimentioning

confidence: 99%

Section: Ferumoxytol’s Characteristics In Mrimentioning

confidence: 99%

Unveiling the next generation of MRI contrast agents: current insights and perspectives on ferumoxytol-enhanced MRI

Si,

Du,

Tang

et al. 2024

National Science Review

View full text Add to dashboard Cite

show abstract

MRI Advancements in Musculoskeletal Clinical and Research Practice

et al. 2023

View full text Add to dashboard Cite

3D MR neurography with gadolinium contrast to improve the visualization of pelvic nerves and the branches

Liu,

Xiao,

Tao

et al. 2024

Front. Physiol.

View full text Add to dashboard Cite

ObjectiveTo evaluate the effectiveness of 3D NerveVIEW sequence with gadolinium contrast on the visualization of pelvic nerves and their branches compared to that without contrast.MethodsParticipants were scanned twice using 3D NerveVIEW sequence with and without gadolinium contrast to acquire pelvic nerve images. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and contrast ratio of the nerves were calculated and compared to determine the quality of images. To subjectively assess, using a 3-point scale, branch nerves critical to therapeutic decision-making, including the pelvic splanchnic nerve and pelvic plexus, the superior gluteal nerve, and the pudendal nerve.ResultsIn the 32 eligible participants after using contrast, the CNRs of the images of nerve-to-bone and nerve-to-vessel significantly increased (p < 0.05). The CR of the images with contrast of all nerve-to-surrounding tissues (i.e., bone, muscle, blood vessels, and fat) were also found significantly higher (p < 0.05). The assessment of observers also shows higher scores for images with contrast compared to images without contrast.ConclusionThe 3D NerveVIEW sequence combined with gadolinium contrast improved vascular suppression, increased the contrast between pelvic nerves and surrounding tissue, and enhanced the visualization of nerves and their branches. This study may be helpful for the technically challenging preoperative planning of pelvic diseases surgery.

show abstract

Three-dimensional MR Neurography of the Brachial Plexus: Vascular Suppression with Low-dose Ferumoxytol

Cited by 3 publications

References 18 publications

Unveiling the next generation of MRI contrast agents: current insights and perspectives on ferumoxytol-enhanced MRI

Unveiling the next generation of MRI contrast agents: current insights and perspectives on ferumoxytol-enhanced MRI

MRI Advancements in Musculoskeletal Clinical and Research Practice

3D MR neurography with gadolinium contrast to improve the visualization of pelvic nerves and the branches

Contact Info

Product

Resources

About