Three-Component Reaction of Triphenylphosphine, Dialkyl Acetylenedicarboxylate, and 2-Aminothiazole or 2-Aminobenzothiazole in the Presence of Arylglyoxals: An Efficient One-Pot Synthesis of Highly Functionalized Pyrroles

Three-Component Reaction Between Indan-1,2,3-trione2-Oxime and Acetylenic Esters in the Presence of Triphenylphosphine

“…The structures of compounds (3a-c) were deduced from their elemental analyses and their IR, 1 H NMR, 13 C NMR spectra. The mass spectra of these compounds displayed molecular ion peaks at appropriate m/z values.…”

“…N-Heterocycles receive considerable attention in the literature as a consequence of their exciting biological properties and their role as pharmacophores 7 . In continues of our previous works on the reaction between phosphorus nucleophiles and acetylenic esters in the presence of organic acids [8][9][10][11][12][13][14][15][16] . We decided to investigate the reaction of OH-acidic compound such as indan-1,2,3-trione 2-oxime 1 with acetylenic esters in the presence of triphenylphosphine.…”

PPh3-Mediated One-Pot Synthesis of Functionalised 4-oxo-4H-benzo[4,5]imidazo[1,2,a]pyrimidines

“…[4][5][6][7] In fact, in these reactions nucleophilic the triphenylphosphine brought together two electrophilic substrates. In continuation of our previous work, on the reaction between phosphorus nucleophiles and acetylenic esters in the presence of organic acids, [8][9][10][11][12][13][14][15] we decided to investigate the reaction of NH-acidic compounds such as methyl benzimidazole-2-yl carbamate 3 with acetylenic esters in the presence of triphenylphosphine.…”

Synthesis of N-(3-alkyl-4-phenyl-3H-thiazol-2-ylidene)Benzamide Derivatives by Reaction of Phenacyl Bromide and Aroyl Isothiocyanates in the Presence of Primary Amines

“…5 Other methods have been reported for the synthesis of thiazoles. [6][7][8][9][10][11][12] As a part of studies on the development of new routes in organic synthesis, [13][14][15][16][17][18][19] I now report an efficient one-pot synthesis of N-(3-alkyl-4-phenyl-3H-thiazol-2-ylidene)benzamide derivatives employing readily available starting materials.…”