Three Cases of Rothia dentocariosa Bacteraemia: Frequency in Denmark and a Review

Abstract

Three cases of non-endocarditis-associated Rothia dentocariosa bacteraermia occurred in Viborg County within the space of a year, whereas no cases have been registered in other parts of Denmark during the last 10 y. Two patients wore dentures but had no history of oral infection, while in the last patient a tooth abscess was detected on examination. R. dentocariosa is a common inhabitant of the oral cavity and the causative agent of a wide spectrum of infectious symptoms. It is only rarely identified in blood cultures, possibly due the inadequacy of the available identification methods.

A First Report of <i>Rothia aeria</i> Endocarditis Complicated by Cerebral Hemorrhage

“…The R. aeria strain that we detected was not susceptible to clindamycin or vancomycin, neither of which had been given to the patient. In addition, R. dentocariosa is reportedly not resistant to clindamycin or vancomycin (14); however, Salamon et al reported that the minimum inhibitory concentration (MIC) of vancomycin for a particular strain of R. dentocariosa determined using an Etest is 3 μg/mL (18). If vancomycin, which is usually used in empirical therapy for infective endocarditis caused by Gram-positive organisms, had been prescribed to the patient during hospitalization, the efficacy would have been poor due to the organism's lack of susceptibility to this drug.…”

Identification of Some Charcoal-Black-Pigmented CDC Fermentative Coryneform Group 4 Isolates as Rothia dentocariosa and Some as Corynebacterium aurimucosum : Proposal of Rothia dentocariosa emend. Georg and Brown 1967, Corynebacterium aurimucosum emend. Yassin et al. 2002, and Corynebacterium nigricans Shukla et al. 2003 pro synon. Coryneb

“…In a recent review of R. dentocariosa bacteremia and endocarditis cases, the authors suggested this rarity may be attributed to lack of awareness and inadequate identification methods (12). In the present study, two of eight of charcoal-black-pigmented Rothia-like isolates were from blood specimens, which emphasizes the pathogenic potential of R. dentocariosa.…”

Rothia aeria Neck Abscess in A Patient with Chronic Granulomatous Disease: Case Report and Brief Review of the Literature

“…Most reported cases are due to infections with R. dentocariosa , followed byinfections with R. mucilaginosa . R. dentocariosa has been associated with severediseases such as endocarditis [7] and bacteremia [8], peritonitis (especially in the peritoneal dialysis population)[9], pneumonia [10], septic arthritis [11], and ocular infections such as corneal ulcers [12] and endopthalmitis [13]. R. mucilaginosa is less commonly reported, but has been associated with bacteremia [14], peritonitis [15], meningitis [16], pneumonia [17], and septic arthritis [18].…”