Third cranial nerve paralysis associated with hypothyroidism

A Case of Sheehan's Syndrome that Manifested as Bilateral Ptosis

“…Ptosis has been previously reported in patients with primary hypothyroidism, but there have been only a few case reports (3-5). In patients with hypothyroidism, myopathy, mononeuropathy and diffuse peripheral polyneuropathy may encountered with various incidences (8).…”

“…Although neuromuscular complications are well recognized in thyroid disorders, their pathophysiology remains unclear. Generally, these abnormalities are secondary to mucopolysaccharide infiltration of various peripheral organs (5). Cho et al (9) described a case of pituitary apoplexy with Sheehan's syndrome and isolated third cranial nerve palsy.…”

“…Hypothyroidism can cause a variety of signs and symptoms of the neuromuscular system (2). However, in the absence of other obvious etiologies, ptosis in a patient with hypothyroidism is very rare (3-5). We report here on a case of central hypothyroidism that was due to Sheehan's syndrome and the patient manifested with bilateral ptosis, and the patient was initially suspected as having myasthenia gravis.…”