A Case of Sheehan's Syndrome that Manifested as Bilateral Ptosis

Lee, Young Sil; Moon, Seong Su

doi:10.3346/jkms.2011.26.4.580

Cited by 5 publications

(3 citation statements)

References 11 publications

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“…Sheehan's syndrome or adenohypophyseal ischemic necrosis occurs following hypoperfusion as a result of ischemic pituitary necrosis due to severe postpartum hemorrhage [7][8][9][10]. Prolactinmediated anterior pituitary hypertrophy during pregnancy seems to render the gland susceptible to ischemic necrosis in the presence of hypovolemic shock, and it is most frequently associated with hemorrhagic shock in the latter stages of labor.…”

Section: Discussionmentioning

confidence: 99%

Co-presentation of Acute Sheehan Syndrome with Raised Intracranial Pressure in a Post-partum Lady

Gomes¹

2021

J Neurol Res Rev Rep

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Sheehan’s syndrome (SS) or necrosis of pituitary gland is a rare complication of severe postpartum hemorrhage. It may cause hypopituitarism immediately or several years later, depending on the degree of tissue destruction. Sheehan’s syndrome though rare is still one of the commonest causes of hypopituitarism in developing countries like ours. The presence of an intercurrent infection and administration of thyroxine exacerbated her corticosteroid insufficiency. Intracranial hypertension (IH) manifested as bilateral optic disc swelling with reduced visual acuity, bilateral sixth nerve palsies, and impaired consciousness. Intracranial hypertension (IH) has been associated with hypocortisolism caused by either primary adrenocortical insufficiency or corticosteroid withdrawal. The author describes a case of a young lady with IH with acute SS who presented on 3rd day postpartum after lower uterine cesarean section with acute severe symptomatic hyponatremia which was complicated by postpartum hemorrhage. The clinical manifestations of IH resolved with corticosteroid replacement

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Section: Discussionmentioning

confidence: 99%

Co-presentation of Acute Sheehan Syndrome with Raised Intracranial Pressure in a Post-partum Lady

Gomes¹

2021

J Neurol Res Rev Rep

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“…Sheehan syndrome exhibits partial or complete hypopituitarism caused by ischemic pituitary necrosis due to obstetrical shock, accompanied by DIC following severe postpartum hemorrhage [4]. However, it is difficult to predict the possible onset of Sheehan syndrome in patients suffered from massive hemorrhage during delivery, while most cases had mild hypopituitarism and failed to be diagnosed for a long time [5].…”

Section: Discussionmentioning

confidence: 99%

A successful pregnant outcome in patient with Sheehan syndrome: a case report

Wang¹,

Zhu²,

Wang³

2017

Clin. Exp. Obstet. Gynecol.

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Sheehan syndrome, which is defined as hypopituitarism, is usually caused by massive postpartum hemorrhage. Hormone replacement therapy is recommended in patients with Sheehan syndrome. It is rare that pregnancy occurs in a patient with Sheehan syndrome, which is associated with high risk of maternal and fetal mortality. The authors report a 36-year-old twin pregnancy with Sheehan syndrome after the first pregnancy. She was treated with adequate management by obstetrician and endocrinologist cooperation during the pregnancy and delivery and had a successful outcome of this pregnancy. This case highlights the importance of proper management for the outcome of pregnancy in patients with Sheehan syndrome.

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“…Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to severe postpartum hemorrhage [ 7 – 10 ]. Only a small proportion of patients with Sheehan's syndrome may have a sudden onset of severe hypopituitarism immediately after delivery, whereas most patients have mild illness and they have not been diagnosed for a long time so that they are not treated appropriately [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report

Hao

Zhang

2012

Case Reports in Medicine

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Sheehan's syndrome, which is pituitary necrosis after severe postpartum hemorrhage and hypovolemia, may cause hypopituitarism immediately or several years later, depending on the degree of tissue destruction. We report an unusual case, in which a 55-year-old woman with Sheehan's syndrome got worse symptoms after spontaneous labor. In 1998, she had severe postpartum hemorrhage and pituitary necrosis during the third delivery, thus it was diagnosed as Sheehan's syndrome by clinical manifestations, laboratory tests, and magnetic resonance imaging. She was treated by replacement therapy including hydrocortisone and levothyroxine sodium. However, she had the fourth spontaneous pregnancy in 2000 and got worse symptoms after delivery. We carefully concluded that pregnancy provided no evidence against the diagnosis of Sheehan's syndrome because pregnancy might improve hypopituitarism by stimulating the pituitary remnant to undergo hyperplasia and irritating the placenta to secrete hormone. However, pregnancy might aggravate the symptoms by inducing autoimmunity as well. All in all, early diagnosis and adequate medical treatment are important to provide a good prognosis of Sheehan's syndrome.

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A Case of Sheehan's Syndrome that Manifested as Bilateral Ptosis

Cited by 5 publications

References 11 publications

Co-presentation of Acute Sheehan Syndrome with Raised Intracranial Pressure in a Post-partum Lady

Co-presentation of Acute Sheehan Syndrome with Raised Intracranial Pressure in a Post-partum Lady

A successful pregnant outcome in patient with Sheehan syndrome: a case report

The Symptoms Get Worse after Pregnancy in Sheehan's Syndrome: A Case Report

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