Thiourea monoanion and dianion complexes of rhodium(III) and ruthenium(II)

On the cytotoxic activity of Pd(II) complexes of N,N-disubstituted-N′-acyl thioureas

“…These data suggest the formation of [Pd(PPh 3 )(Cl)(L)] for complex (1) and [Pd(PPh 3 ) 2 (L)] PF 6 for complexes (2-7), in which L represents the anionic ligand formed upon deprotonation, when the N,N-disubstituted-N′-acyl thioureas coordinate to the metal center.…”

“…Chelating thiourea ligands containing N, S and O donor atoms show broad biological activity and the existence of metal ions bonded to biologically active compounds may enhance their activities, and it was shown that the mode of binding of platinum to DNA is affected by the substituent nature on the acyl thiourea [4]. Acyl thiourea derivatives have been increasingly important with a wide diversity of applications in heterocyclic chemistry, metal complexes, molecular electronics and exhibit an array of biological activities [5][6][7][8][9]. Some of them are employed as fungicidal, antiviral, antimicrobial [10], parasiticidal [11], antitumoral [12] and pesticidal agent [13][14][15].…”

Crystal structure of cis-copper(II) complex with N-(di-n-propylcarbamothioyl)cyclohexanecarboxamide ligand

“…At the same time some of them are display a wide range of biological activity including insecticidal, herbicidal, antibacterial, antifungal, antitubercular, antithroid, antihelmintic, rodenticidal and plant-growth regulator properties [7][8][9][10]. Thiourea derivative ligands are tend to coordinate to both transition group and main group metal ions via both sulfur and oxygen providing a multitude of bonding possibilities [11][12][13]. Copper(II) complexes of acyl thiourea ligands have been described repeatedly in the literature with regard to their synthesis and general characterization [14][15][16] and molecular structures [17][18][19][20].…”

Enhanced Anion Binding from Unusual Coordination Modes of Bis(thiourea) Ligands in Platinum Group Metal Complexes

“…The remaining NH group of N(1) forms a hydrogen bond to the opposite face of the chloride anion and as a result the complex in the solid state forms a centrosymmetric hydrogen-bonded dimer linked by interactions to the chloride anions (Figure 1b). A bidentate, N,S-coordination mode has been seen in a number of deprotonated monothiourea derivatives of ruthenium, [88,89] platinum(II), [90,91] cadmium, [92] zinc, [93] goldA C H T U N G T R E N N U N G (III) [94] and gold(I). [95] The N,S-thioureido chelate binding mode is also observed for complexes with rhenium(V) in a thiol-amide-thiourea ligand, [96] and it is found in both coordinating thioureas for an analogous bis-A C H T U N G T R E N N U N G (thiourea) ligand.…”