Thiosemicarbazone@Gold nanoparticle hybrid as selective SERS substrate for Hg2+ ions

Franciscato, Douglas S.; Matias, Tiago A.; Shinohara, Jorge S.; Gonçalves, Josué M.; Coelho, Narcimário Pereira; Fernandes, Cleverton S.; Basso, Ernani A.; Nakatani, Helena S.; Araki, Koji; Toma, Henrique E.; Souza, Vagner Roberto de

doi:10.1016/j.saa.2018.06.038

Cited by 12 publications

(6 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The lowest concentration for quantitative detection of Hg 2+ by this method corresponded to 1 nM, which is lower than the allowable maximum residue limit of Hg 2+ (10 nM) in drinkable water as per the United States Environmental Protection Agency (USEPA). 33,38 Compared with the previously reported methods for Hg 2+ measurement, 39–43 the proposed strategy for Hg 2+ shows much higher detection sensitivity (Table S2†).…”

Section: Resultsmentioning

confidence: 90%

Tetrahedral DNA-directed core-satellite assembly as SERS sensor for mercury ions at the single-particle level

Feng

Shen

et al. 2022

Analyst

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 90%

Tetrahedral DNA-directed core-satellite assembly as SERS sensor for mercury ions at the single-particle level

Feng

Shen

et al. 2022

Analyst

View full text Add to dashboard Cite

show abstract

“…As shown in Figure S8 of the Supporting Information, the Raman peak registered at 320 cm –1 is assigned to the symmetric ν(Au–S) stretch . After Hg 2+ addition, the Raman bands corresponding to the symmetric stretching of Hg–S appear at 255 and 291 cm –1 . , Thus, it is plausible that reduced Hg could interact simultaneously with the AuNRs and the sulfur atom through the Au–Hg–S bond. , In addition, the introduction of AA solution initially caused a slight redshift (from 630 to 635 nm) in the LSPR peak for 1-hexadecanethiol-coated AuNRs under low Hg 2+ conditions, presumably because excess AA exchanged a portion of CTAB that was not completely replaced during mercaptan modification . The TEM images in Figure S7 of the Supporting Information show the 1-hexadecanethiol-coated AuNRs in the absence of Hg 2+ as well as at medium and high concentrations.…”

Section: Resultsmentioning

confidence: 97%

“…Both reducing agents caused slight hypochromatic shifts in the LSPR peaks and did not merge with the TSPR peak of 1-hexadecanethiol-coated AuNRs (panels A and E of Figure S7 of the Supporting Information). Even though NaBH 4 could displace the thiol molecules adsorbed on the AuNRs, the thiol molecules also bond to the mercury (Au–Hg–S) on the surface of the AuNRs (Figure S8 of the Supporting Information), preventing the diffusion of mercury and maintaining the original morphology of the AuNRs . To evaluate this hypothesis, the corresponding Raman spectra were recorded.…”

Section: Resultsmentioning

confidence: 99%

“…On the basis of the reducing ability of AA, Hg 2+ was reduced to Hg around the AuNRs. The penetration of Hg into the interior of the AuNRs was suppressed, possibly because the AA molecules on the surface of the AuNRs formed Au–Hg–AA bonds, which hindered the diffusion of mercury . As the above reduction process occurs, reduced Hg in the solution could be stabilized by CTAB.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

How Stabilizers and Reducing Agents Affect the Formation of Nanogold Amalgams

Wang

Cao

et al. 2021

Langmuir

View full text Add to dashboard Cite

The influence of mercury on the morphology and formation mechanism of gold amalgams in the presence of different reducing agents (ascorbic acid and sodium borohydride) was systematically studied. In the presence of cetyltrimethylammonium bromide (CTAB), chemical reducing agents not only reduced mercury ions in the solution but also replaced the CTAB molecules on the surface of the gold nanorod. The stability of the reducing agents in the colloidal system and the combining capacity of the reducing agent to the gold nanoparticles can affect the alloying process of mercury and gold, thereby forming a rod-shaped or spherical gold amalgam. Once CTAB was removed, a similar transformation process occurs between the gold nanorods and mercury. In addition, without the presence of a stabilizer, mercury that cannot be dispersed undergoes Ostwald ripening growth, which causes the gold amalgam nanoalloys to form a tip-to-tip structure as a result of mercury enrichment because of the weak shielding effects occurring at the tips of the gold nanorods. After the CTAB molecules were substituted with ascorbic acid and alkylthiol molecules, the question of whether the shielding effect weakened or disappeared was also investigated. By investigation, this research found that, in comparison to the blocking effect of CTAB molecules, the binding ability of the reducing agent to gold plays a dominant role in the nanoamalgam formation process.

show abstract

“…In contrast to this, the idea of binding metal-TSC complexes or [drug-TSC] conjugates to surfaces of NP is new [41][42][43]. The potential suitability of TSCs to serve as ligands for metal coordination covalently anchored on NP surfaces and conjugating them to further functional units at the same time, is obvious from the up to four possible substituents on both the N1 and N4 functions of the general TSC R1R2C=N(1)-NH-C(S)-N(4)R3R4 backbone (Scheme 1A and B, marked in green) and from the modular synthesis from the R3-and R4-substituted thiosemicarbazides and any R1-and R2substituted carbonyl (Scheme 1D, blue and red marking, respectively).…”

Section: Introductionmentioning

confidence: 99%

Functionalizing Thiosemicarbazones for Covalent Immobilization on Nanoparticles

Hohnsen,

Rryci,

Obretenova

et al. 2024

Preprint

View full text Add to dashboard Cite

The use of thiosemicarbazones (TSCs) as ligands for the functionalization of nanoparticles (NP) for various purposes, such as the covalent immobilization is fueled by their modular character (thiosemicarbazides + carbonyl compound), allowing enormously broad variation of up to four substituents on the main R1R2C=N(1)–NH–C(S)–N(4)R3R4 core. For R1 and R2 we introduced di-2-pyridyl ketone for the coordination of metals and 9-anthraldehyde for luminescence. R3 and R4 substituents were varied for various purposes. Amino acids were functionalized at the N4 position to [R1R2TSC–spacer–amino acid] conjugates for future peptide conjugation or for direct anchoring to NP via their carboxylic function. Further direct NP anchoring functions such as phosphonic acid (OP(OH)2), glucose, o-hydroquinone, OH, and thiol (SH) were introduced with or without separation through hydrocarbon spacer units such as phenyl, cyclohexyl, benzyl, ethyl and methyl in [R1R2TSC–spacer–anchor group] conjugates. [R1R2TSC–spacer–end group] conjugates including OH, S-Bn (Bn = benzyl), NH-Boc (Boc = tert-butyloxycarbonyl), COOtBu, or N3 end groups were produced for the facile formation of amide, ester, or triazine conjugates through click chemistry. The synthesis of the thiosemicarbazides H2NH–C(S)–NR3R4 starting from amines, including amino acids, SCCl2 or CS2, and hydrazine and their condensation with dipyridyl ketone and anthraldehyde lead finally to 34 new TSC derivatives. They were synthesized in up to six steps with overall yields ranging from 10 to 85% and were characterized by a combination of elemental analyses, mass spectrometry, and magnetic nuclear resonance spectroscopy. UV-vis absorption and photoluminescence spectroscopy allowed to easily trace the dipyridyl imine and anthracene chromophores.

show abstract

Thiosemicarbazone@Gold nanoparticle hybrid as selective SERS substrate for Hg2+ ions

Cited by 12 publications

References 38 publications

Tetrahedral DNA-directed core-satellite assembly as SERS sensor for mercury ions at the single-particle level

Tetrahedral DNA-directed core-satellite assembly as SERS sensor for mercury ions at the single-particle level

How Stabilizers and Reducing Agents Affect the Formation of Nanogold Amalgams

Functionalizing Thiosemicarbazones for Covalent Immobilization on Nanoparticles

Contact Info

Product

Resources

About