Tetrahedral DNA-directed core-satellite assembly as SERS sensor for mercury ions at the single-particle level

Abstract

Facing deteriorating mercury emissions, it is imperative to propose methods for detecting mercury ions (Hg2+) with sensitivity and selection. The SERS spectral-resolved single-particle detection approach can be carried out by...

Advancements in mercury detection using surface-enhanced Raman spectroscopy (SERS) and ion-imprinted polymers (IIPs): a review

“…86 The high affinity of Hg 2+ to thymidine is exploited to induce hybridization or conformational changes in DNAs tethered on the surface of metal NPs, offering control of interparticle distance. 86 The strategy produces either a turn-on or turn-off SERS signals. selectivity and sensitivity due to the affinity of Hg 2+ to thymidine and the strong electromagnetic field generated due to plasmonic coupling of NP assemblies.…”

“…Hybrid Substrates of Solid-SERS for Enhanced Precision in Hg2+ Ion Detection Solid-SERS substrates merged with colloidal or electrochemical approaches is shown to provide enhanced precision in Hg 2+ detection. In the study by Feng et al, a tetrahedral DNA structures was utilized in constructing a solid-colloidal hybrid substrate sensor that is superior in terms of selectivity, sensitivity, and stability compared to sensing approaches employing either colloidal or solid SERS substrates alone 86. The hybrid SERS substrate was composed of satellite AuNPs tethered by tetrahedral DNA structures to a core AuNP supported on indium tin oxide (ITO).One edge of the tetrahedron featured single-stranded DNA containing an Hg 2+ aptamer.…”

A novel dual-mode aptasensor based on a multiple amplification system for ultrasensitive detection of lead ions using fluorescence and surface-enhanced Raman spectroscopy

“…10,11 As a multifunctional nanomaterial, gold nanoparticles (AuNPs) have been widely used as active substrates in SERS sensors based on their "hot spot" effect, [12][13][14][15] and the distance between the signal molecules and the surface of the AuNPs controls the enhancement/reduction of the SERS signal. 16,17 On the other hand, when the signal molecules are sufficiently close to the surface of the AuNPs (<5 nm), their fluorescence (FL) will be significantly quenched thanks to the nonradiative decay through energy and/or charge transfer to the AuNPs. [18][19][20] The unique optical and electrical properties of AuNPs provide feasibility for constructing sensors with integrated SERS and FL dual signal responses, which is of great significance for improving the anti-interference ability of sensing systems.…”

Identification and classification of particle contaminants on photomasks based on individual-particle Raman scattering spectra and SEM images

“…[19][20][21] Raman shi corresponds to the vibration or rotation mode of the corresponding chemical bond, which can realize the detection and identication of the small particle. [22][23][24][25] It is therefore of great advantage in the analysis of the structure of compounds. E. M. Malykhin et al investigated the structure and chemical properties of carbon lms under 13.5 nm UV irradiation using Raman and IR spectroscopy, respectively.…”