Thiophosgene

Abstract

was born in 1980 in Oaxaca, Mexico. She graduated from Benemérita Universidad Autónoma de Puebla in 2003 and received her M.Sc. degree in organic chemistry in 2006. Currently, she is working under the supervision of Dr. Sara Montiel Smith. Her Ph.D. research project focuses on the development of novel methodologies to construct steroidal heterocyclic frameworks with the aim of finding new bioactive molecules.

Triton-B Mediated One-Pot Multicomponent Synthesis of 3,5 Substituted Tetrahydro-2H-1,3,5-Thidiazine-2-Thiones

“…In the present work, series of substituted THTT (1a-15a) are synthesized by Triton B mediated one-pot multicomponent reaction, a novel protocol (Scheme 2). Earlier THTT was produced from amines, CS 2 , formaldehyde using inorganic base [23][24][25] . A number of PTC is frequently used for the synthesis of THTT 26 .…”

H2O‐Mediated Epoxide Ring‐Opening with Concomitant C–S Bond Formation: A One‐Pot Method to 3‐Hydroxy‐oxindolino‐dithiocarbamates as Cytotoxic Agents

“…However, the formation of carbon‐sulphur bond under environmentally benign conditions is an important organic transformation. In addition, the formation of dithiocarbamate involves certain limitation such as the use of toxic reagents, strong bases, long reaction time, low yields which encouraged us to search for more efficient methods for the synthesis of reactive dithiocarbamates from CS 2 and secondary amines. To the best of our knowledge, dithiocarbamate has not yet been explored as nucleophile perticularly in the isatin spiro ‐epoxide ring‐opening –.…”