Thioacetamide induced liver damage in zebrafish embryo as a disease model for steatohepatitis

Molecular cloning, expression, and functional analysis of caspase-10 from Japanese flounder Paralichthys olivaceus

“…The existence of caspase-10 in fish was demonstrated in this study. In addition, caspase-8 has been cloned from medaka and zebrafish [23,30]. While fish diverged from amphibians 350 million years ago and they have established the characteristic immune system to adapt to their living environment, both caspase-8 and caspase-10 have been maintained in fish as well as mammals.…”

Depletion of suppressor of cytokine signaling-1a causes hepatic steatosis and insulin resistance in zebrafish

“…The frozen livers were cryosectioned, and the sections were subjected to hematoxylin and eosin staining. The frozen sections were also stained with Oil Red O to visualize the fat deposits in the liver, as described previously (2). The stained sections were visualized under a light field, and images were captured at different magnifications.…”

Real-Time Imaging of Lipid Metabolism in Larval Zebrafish

“…The zebrafish field abounds with models of human diseases, with zebrafish carrying a mutation in a specific disease gene manifesting phenotypes strikingly similar to those observed in humans. [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] Zebrafish models of human diseases include cardiovascular diseases (reviewed in Ref. 29), Duchenne muscular dystrophy, 30 various cancers (reviewed in Ref.…”