Thickness of the retinal nerve fiber layer in amblyopic and normal eyes: A scanning laser polarimetry study

The effect of anisometropic amblyopia on retrobulbar blood flow parameters

“…In another study, scanning laser polarimetry was performed on patients with unilateral strabismic or anisometropic amblyopia. There was no statistical significant difference in thickness of the RNFL between the amblyopic and fellow eye [6]. Huynh et al [8] reported that in children aged between 6 and 12 years, central macular thickness was higher in amblyopic eyes.…”

“…Although amblyopia has been defined as low visual acuity in one eye with a structurally normal globe, it has now been established that the amblyopic eye may have some subtle structural anomalies including changes to retinal ganglion cells, the retinal nerve fiber layer (RNFL), and the optic nerve (ON) [2][3][4][5][6][7][8][9].…”

Retinal Alterations Detected Using Optical Coherence Tomography in Children with Strabismus

“…These studies did not reported statistically meaningful difference in iNFA-GDx parameters between normal and amblyopic eyes. [9] In respect to these data, we compared retinal nerve fiber thickness of strabismus patients with or without amblyopia with healthy children. We attempted to determine the value of OCT as an early identification method in the diagnoses of strabismic amblyopia through assessing the changes in RNFL in strabismus.…”

OCT Changes In Unilateral Amblyopia Patients, Using OPKOS SLO/OCT: A Cross Sectional Study

“…Functional changes are well documented in amblyopia, including loss of visual acuity and contrast sensitivity. As for structural changes, the deleterious effect of amblyopia on the cell growth of the lateral geniculate body (Baddini-Caramelli et al, [2] and visual cortex (Dyer D et al (1952) [3] has been well-established by quantitative histologic studies in several animal species and in human, but retinal involvement in amblyopia is still a topic of debate worldwide, with different studies showing conflicting results. During fetal development, there is a rapid decline in cell density in the retinal ganglion cell layer toward the end of gestation.…”