Thermodynamic study of β-cyclodextrin-dye inclusion complexes using gradient flow injection technique and molecular modeling

Synthesis and Characterization of Host Guest Inclusion Complexation of Cyclic Oligosaccharide with Industrially Potent Dye in Different Phases by Physicochemical Contrivance

“…2D ROESY NMR is a technique for investigating the spatial proximity between the host and the guest moieties by observation of intermolecular dipolar cross‐correlations . In NOESY or ROESY spectroscopy, when two protons are located in space closer than 4 Å able to produce a nuclear overhauser effect (NOE) cross peaks . Figure 1. shows the 2D spectrum of AC.β‐CD inclusion complex in which only a single intermolecular NOE cross‐peak was observed.…”

“…β‐cyclodextrin (β‐CD) consists of a truncated cone‐shaped structure. It has a cavity size of 7.9 Å depth and top and bottom diameters are of 6.0 and 6.5 Å respectively . When dissolved in an aqueous medium, the cavity of β‐cyclodextrin molecule gets occupied by 8–9 water molecules, which are excluded from the cavity, after its complexation with a well‐fitted guest molecule .…”

“…The inclusion complexes are capable of modifying both the chemical and physical properties of guest molecules, such as solubility, spectroscopic features and chemical properties and such modified forms have widespread applications in food industry, pharmaceutical industries (to boost the stability, bioavailability and persistance of the chemicals and these can also slow down the release of active compounds from pharmaceutical matrix), drug delivery technology, food industry, medicine, agriculture, textile industry etc. In textile industry, cyclodextrins act as defoaming agents by forming inclusion complexes with different detergent molecules …”

“…It has a cavity size of 7.9 Å depth and top and bottom diameters are of 6.0 and 6.5 Å respectively. [1,2,3,4] When dissolved in an aqueous medium, the cavity of β-cyclodextrin molecule gets occupied by [8][9] water molecules, which are excluded from the cavity, after its complexation with a well-fitted guest molecule. [5] The presence of the α-1,4-linkage of each glucopyranose unit makes all of the hydrophilic 2-, 3-, and 6-hydroxyl groups to be located at the exterior part of the hydrophobic cavity.…”

“…In textile industry, cyclodextrins act as defoaming agents by forming inclusion complexes with different detergent molecules. [1,2] Dyes have become the topic of utmost interest of the researchers in recent years because of increasingly demanding restrictions on the organic content of industrial sewages. These are well known as the most common water pollutants and often found in trace quantities in industrial wastewater.…”