Thermodynamic models for determination of the solid–liquid equilibrium of 2,5-thiophenedicarboxylic acid in (acetic acid + ethanol) binary solvent mixtures

Hu, Yonghong; Yang, Yang; Cao, Yang; Li, Yonglan; Yang, Wenge; Cheng, Limin

doi:10.1016/j.fluid.2015.06.007

Cited by 3 publications

(1 citation statement)

References 19 publications

(22 reference statements)

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“…The magnetic stirrer was used to stir continuously at the required temperature to ensure the suspension to mix evenly. In order to ensure solid–liquid equilibrium, the solution was precipitated for more than 12 h and reached a static state before sampling. − Solvent evaporation was prevented by using a condenser in the measurement process. All beakers with a volume of a saturated solution were placed in an oven with a temperature of 25 °C and weighed daily until constant weight was reached.…”

Section: Methodsmentioning

confidence: 99%

Determination and Correlation of Solubility of Carvedilol in Six Pure Solvents and Three Binary Solvent Mixtures at T = 278.15–313.15 K

Wang

et al. 2020

J. Chem. Eng. Data

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Carvedilol is a drug for the treatment of congestive heart failure whose solubility in solvent and crystallization process are poorly understood. In this study, the solubilities of carvedilol in water, ethanol, acetone, tetrahydrofuran, methyl alcohol, ethyl acetate, (water + ethanol), (water + acetone), and (water + tetrahydrofuran) binary mixtures were measured in the temperature range from 278.15 to 313.15 K under atmospheric pressure by the gravimetric method. The experimental values have indicated that increasing temperature can improve the solubility of carvedilol in all selected binary solvents. To correlate the solubility data of carvedilol, the Buchowski–Ksiazaczak λh model was used to fit the solubility data of all pure solvents, while the solubility data of all binary solvent mixtures were fitted by the modified Apelblat equation, general cosolvency model, and Jouyban–Acree model. The results show that the modified Apelblat equation in binary mixed solvents has the lowest mean deviation and can be used as the optimal model for data fitting.

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Section: Methodsmentioning

confidence: 99%

Determination and Correlation of Solubility of Carvedilol in Six Pure Solvents and Three Binary Solvent Mixtures at T = 278.15–313.15 K

Wang

et al. 2020

J. Chem. Eng. Data

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Thermodynamic models for determination of the solid–liquid equilibrium of oxytocin in (acetonitrile+acetone) binary solvent mixtures

Zhang

Shen³

et al. 2016

Fluid Phase Equilibria

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Thermodynamic models for determination of the solid-liquid equilibrium of istradefylline in ethyl acetate plus (isopropanol, tetrahydrofuran, acetone) binary solvent mixtures

Huang

Ling³

et al. 2017

The Journal of Chemical Thermodynamics

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Thermodynamic models for determination of the solid–liquid equilibrium of 2,5-thiophenedicarboxylic acid in (acetic acid + ethanol) binary solvent mixtures

Cited by 3 publications

References 19 publications

Determination and Correlation of Solubility of Carvedilol in Six Pure Solvents and Three Binary Solvent Mixtures at T = 278.15–313.15 K

Determination and Correlation of Solubility of Carvedilol in Six Pure Solvents and Three Binary Solvent Mixtures at T = 278.15–313.15 K

Thermodynamic models for determination of the solid–liquid equilibrium of oxytocin in (acetonitrile+acetone) binary solvent mixtures

Thermodynamic models for determination of the solid-liquid equilibrium of istradefylline in ethyl acetate plus (isopropanol, tetrahydrofuran, acetone) binary solvent mixtures

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