2019
DOI: 10.1016/j.bios.2019.111581
|View full text |Cite
|
Sign up to set email alerts
|

Thermally stable and uniform DNA amplification with picosecond laser ablated graphene rapid thermal cycling device

Abstract: Rapid thermal cycling (RTC) in an on-chip device can perform DNA amplification in vitro through precise thermal control at each step of the polymerase chain reaction (PCR). This study reports a straightforward fabrication technique for patterning an on-chip graphene-based device with hole arrays, in which the mechanism of surface structures can achieve stable and uniform thermal control for the amplification of DNA fragments. A thin-film based PCR device was fabricated using picosecond laser (PS-laser) ablatio… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2021
2021
2023
2023

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
(1 citation statement)
references
References 76 publications
0
1
0
Order By: Relevance
“…In the past, both methods could be applied to detect both small polar molecules and larger peptides, as well as proteins in biological materials [ 94 , 95 , 96 ]. Intact DNA molecules could also be removed from organic materials using an IR laser [ 97 ]. At the present time, it is difficult to estimate whether a transfer of such a technical strategy to old materials is possible and how high the information content is in comparison to the other methods presented since there is currently no experience in this regard.…”
Section: Sampling Strategiesmentioning
confidence: 99%
“…In the past, both methods could be applied to detect both small polar molecules and larger peptides, as well as proteins in biological materials [ 94 , 95 , 96 ]. Intact DNA molecules could also be removed from organic materials using an IR laser [ 97 ]. At the present time, it is difficult to estimate whether a transfer of such a technical strategy to old materials is possible and how high the information content is in comparison to the other methods presented since there is currently no experience in this regard.…”
Section: Sampling Strategiesmentioning
confidence: 99%