Thermal decomposition of nickel(II), palladium(II), and platinum(II) complexes of N-allyl-N′-pyrimidin-2ylthiourea

Katib, S. M. A.

doi:10.1007/s10973-010-1009-0

Cited by 8 publications

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The thermal behavior of 4MTU and 6MTU Copper(I) compounds recorded from ambient temperature up to 600 C in nitrogen flow do not show any loss in weight up to 190 C, reveals that crystal water molecules and coordinated water molecules are not present in the compounds [40]. The TG curves in the 190e400 C range suggest that the loss in weight for complexes 2, 5 corresponds to elimination of 2 molecules of MTU ligand with a DTGmax 258 C. The TG curves in the 190e285 C range suggest that the loss in weight for complex 3, 6 corresponds to elimination of one molecule of MTU ligand with a DTGmax 208 C and 285e560 C range suggest that the loss in weight one molecule of phen with a DTGmax 396 C. In both cases the remaining residues are metal oxides.…”

Section: Tg and Dtamentioning

confidence: 98%

Synthesis, spectroscopic characterisation, thermal analysis, DNA interaction and antibacterial activity of copper(I) complexes with N, N′- disubstituted thiourea

Chetana

Srinatha

Somashekar

et al. 2016

Journal of Molecular Structure

View full text Add to dashboard Cite

copper(I) complexes [Cu(4MTU) 2 Cl] (2), [Cu(4MTU) (B)Cl] (3), [Cu(6MTU) 2 Cl] (5) and [Cu(6MTU) (B)Cl] ( 6) where 4MTU ¼ 1-Benzyl-3-(4-methyl-pyridin-2-yl)-thiourea (1) and 6MTU ¼ 1-Benzyl-3-(6-methylpyridin-2-yl)-thiourea (4), B is a N,N-donor heterocyclic base, viz. 1,10-phenanthroline (phen 3, 6), were synthesized, characterized by various physico-chemical and spectroscopic techniques. The elemental analysis suggests that the stoichiometry to be 1:2 (metal:ligand) for 2, 5 1:1:1 (metal:ligand:B) for 3, 6. Xray powder diffraction illustrates that the complexes have crystalline nature. IR data coupled with electronic spectra and molar conductance values suggest that the complex 2, 5 show the presence of a trigonal planar geometry and the complex 3, 6 show the presence of a tetrahedral geometry about the Cu(I) centre. The binding affinity towards calf thymus (CT) DNA was determined using UV-Vis, fluorescence spectroscopic titrations and viscosity studies. These studies showed that the tested phen complexes 3, 6 bind moderately (in the order of 10 5 M À1 ) to CT DNA. The complex 2, 5 does not show any apparent binding to the DNA and hence poor cleavage efficiency. Complex 3, 6 shows efficient oxidative cleavage of plasmid DNA in the presence of H 2 O 2 involving hydroxyl radical species as evidenced from the control data showing inhibition of DNA cleavage in the presence of DMSO and KI. The in vitro antibacterial assay indicates that these complexes are good antimicrobial agents against various pathogens. Anti-bacterial activity is higher when thiourea coordinates to metal ion than the thiourea alone.

show abstract

Section: Tg and Dtamentioning

confidence: 98%