Thermal Ablation and High-Resolution Imaging Using a Back-to-Back (BTB) Dual-Mode Ultrasonic Transducer: In Vivo Results

Ultrasound transducer devices have their own frequency ranges, depending on the applications and specifications, due to penetration depth, sensitivity, and image resolution. For imaging applications, in particular, the transducer devices are preferable to have a wide bandwidth due to the specific information generated by the tissue or blood vessel structures. To support these ultrasound transducer devices, ultrasound power amplifier hardware with a wide bandwidth can improve the transducer performance. Therefore, we developed a new bandwidth expander circuit using specially designed switching architectures to increase the power amplifier bandwidth. The measured bandwidth of the power amplifier with the help of the bandwidth expander circuit increased by 56.9%. In addition, the measured echo bandwidths of the 15-, 20-, and 25-MHz transducer devices were increased by 8.1%, 6.0%, and 9.8%, respectively, with the help of the designed bandwidth expander circuit. Therefore, the designed architecture could help an ultrasound system hardware with a wider bandwidth, thus supporting the use of different frequency ultrasound transducer devices with a single developed ultrasound system.

Section: Echo Signal Performance Comparison and Analysismentioning

confidence: 99%

Novel Bandwidth Expander Supported Power Amplifier for Wideband Ultrasound Transducer Devices

Kim

Choi

2021

“…In diagnostic ultrasound imaging applications, the ultrasound systems are categorized into transmitters, receivers, and transducers [8][9][10]. Figure 1 shows the transducer, transmitter, and receiver in the ultrasound system used to describe the locations of the components of the preamplifier and time-gain compensation amplifier [11,12].…”

Section: Introductionmentioning

confidence: 99%

Design of Preamplifier for Ultrasound Transducers

Choi

2024

In diagnostic ultrasound imaging applications, preamplifiers are used as first-stage analog front-end amplifiers for ultrasound transducers because they can amplify weak acoustic signals generated directly by ultrasound transducers. For emerging diagnostic ultrasound imaging applications, different types of preamplifiers with specific design parameters and circuit topologies have been developed, depending on the types of the ultrasound transducer. In particular, the design parameters of the preamplifier, such as the gain, bandwidth, input- or output-referred noise components, and power consumption, have a tradeoff relationship. Guidelines on the detailed design concept, design parameters, and specific circuit design techniques of the preamplifier used for ultrasound transducers are outlined in this paper, aiming to help circuit designers and academic researchers optimize the performance of ultrasound transducers used in the diagnostic ultrasound imaging applications for research directions.

“…With the growth of technology, high frequency single element and array transducers have been developed [ 33 , 34 , 35 , 36 , 37 , 38 ]. In particular, the development of an ultrahigh frequency (UHF) transducer over 100 MHz has led to improved ultrasound imaging technologies due to its superior resolution (less than 20 μm) with a low f-number [ 39 ].…”

Section: Introductionmentioning

confidence: 99%

Ultrasonic High-Resolution Imaging and Acoustic Tweezers Using Ultrahigh Frequency Transducer: Integrative Single-Cell Analysis

Jung

Shung

Lim

2023

Self Cite

Ultrasound imaging is a highly valuable tool in imaging human tissues due to its non-invasive and easily accessible nature. Despite advances in the field of ultrasound research, conventional transducers with frequencies lower than 20 MHz face limitations in resolution for cellular applications. To address this challenge, we employed ultrahigh frequency (UHF) transducers and demonstrated their potential applications in the field of biomedical engineering, specifically for cell imaging and acoustic tweezers. The lateral resolution achieved with a 110 MHz UHF transducer was 20 μm, and 6.5 μm with a 410 MHz transducer, which is capable of imaging single cells. The results of our experiments demonstrated the successful imaging of a single PC-3 cell and a 15 μm bead using an acoustic scanning microscope equipped with UHF transducers. Additionally, the dual-mode multifunctional UHF transducer was used to trap and manipulate single cells and beads, highlighting its potential for single-cell studies in areas such as cell deformability and mechanotransduction.