Fundamental Aspects of Cancer 1989
DOI: 10.1007/978-94-009-1089-8_18
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Therapy of Metastasis in Animal Models

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“…A number of compounds, e.g. anticoagulatnts, platelet inhibitors, or antiinvasive compounds have been identified as potential antimetastatic drugs [3][4][5]. Many of them were able to reduce the number of lung colonies after intravenous injection of tumor cells ("artificial metastasis model"), but the majority failed to inhibit metastasis of spontaneously metastasizing tumors, a model system which covers all steps of the metastatic cascade and therefore has a high relevance to the clinic [4,5].…”
Section: O~002 Hmentioning
confidence: 99%
“…A number of compounds, e.g. anticoagulatnts, platelet inhibitors, or antiinvasive compounds have been identified as potential antimetastatic drugs [3][4][5]. Many of them were able to reduce the number of lung colonies after intravenous injection of tumor cells ("artificial metastasis model"), but the majority failed to inhibit metastasis of spontaneously metastasizing tumors, a model system which covers all steps of the metastatic cascade and therefore has a high relevance to the clinic [4,5].…”
Section: O~002 Hmentioning
confidence: 99%