Thérapies cognitives et comportementales après les premiers épisodes psychotiques

Lecardeur, Laurent

doi:10.1016/s0013-7006(13)70106-4

Cited by 9 publications

(3 citation statements)

References 21 publications

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“…Psychotherapy interventions based on a mobile app (psychoeducation, problem solving model, and mindfulness model) have proven to be effective in psychosis, mostly in a face-to-face format (8, 9, 79–82), and this modality might facilitate this type of intervention.…”

Section: Discussionmentioning

confidence: 99%

Mobile App–Based Intervention for Adolescents With First-Episode Psychosis: Study Protocol for a Pilot Randomized Controlled Trial

et al. 2019

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Introduction: Previous studies have shown an improvement in the access to treatment for patients with first-episode psychosis (FEP), specifically young patients, through mobile app–based interventions. The aim of this study is to test the effectiveness of a mobile app–based intervention to improve community functioning in adolescents with FEP. Mobile app–based interventions could increase quality of life and disease awareness, which improve adherence to treatment and reduce the frequency of relapses and rehospitalizations in adolescents with FEP.Methods: This article describes a mobile app treatment and the pilot trial protocol for patients with FEP. We will perform a single-blind randomized clinical trial (RCT) including patients with FEP aged 14–19 years recruited from Gregorio Marañón Hospital, Madrid, Spain. Patients will be randomly assigned to an intervention group, which will receive treatment as usual plus five modules of a psychological intervention through the mobile app (psychoeducation, recognition of symptoms and prevention of relapses, problem solving, mindfulness, and contact wall), or to a control group (standard care). The effectiveness of the intervention will be assessed by means of an extensive battery of clinical tests at baseline and at 3 months of follow-up. The primary outcome is reduction in psychotic and depressive symptoms; secondary outcomes comprise adherence, awareness, use of drugs, and quality of life. Data will be analyzed on an intention-to-treat (ITT) basis. Mixed model repeated-measures analysis will be used to explore the following effect: group × time interaction between the control group and the intervention group for clinical and functional variables during the follow-up period.Discussion: This is an innovative study for the assessment of a psychological intervention through a mobile app for patients with FEP during the critical period. This pilot RCT is intended to be a precursor to larger studies, which in turn could facilitate dissemination of mobile app therapy for patients with FEP.Ethics and Dissemination: The local ethics committee approved the study protocol. All participants must sign the informed consent, to participate. After finalizing the study, the results will be published.Trial registration: NCT03161249. NCT clinicaltrials.gov. Date of registration in primary registry 02 May 2017. clinicaltrials.gov.

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Section: Discussionmentioning

confidence: 99%

Mobile App–Based Intervention for Adolescents With First-Episode Psychosis: Study Protocol for a Pilot Randomized Controlled Trial

et al. 2019

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“…There is a relative heterogeneity of patients with different needs, and so interventions specific to each individual patient are chosen. We offer evidence-based pharmacological treatment, individual cognitivebehavioural therapy for psychosis, and psychoeducation ( Alvarez-Jiménez, Parker, Hetrick, McGorry, & Gleeson, 2011;Hodé, 2013;Lecardeur, 2013). We believe that supporting caregivers and their inclusion in the treatment plan is essential, and so family intervention with a significant psychoeducation component is a cornerstone of the programme (Onwumere, Jansen, & Kuipers, 2018).…”

Section: Introductionmentioning

confidence: 99%

PROFIP: A Portuguese early intervention programme for first‐episode psychosis in Lisbon

Coentre

Mendes

Rebelo

et al. 2019

Early Intervention Psych

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Aim There is currently no national plan for early intervention in first‐episode psychosis in Portugal. Consequently, there is some heterogeneity in the evaluation and treatment of first‐episode psychosis across the country. The aim of this article is to provide a complete description of the early intervention programme Programa de Intervenção nas Fases Iniciais da Psicose (PROFIP) in Lisbon, a pioneering team in Portugal for treating first‐episode psychosis (FEP) patients. We also describe the baseline socio‐demographic and clinical data obtained from new patients over a 1‐year period. PROFIP programme accepts all cases of FEP, taking a transdiagnostic approach. Methods Description of PROFIP programme and baseline socio‐demographic and clinical data obtained from new patients over a 1‐year period. Results The team was constituted to provide early detection, treatment and support to people aged 16 to 35 years with affective and non‐affective FEP. Over a 1‐year period, 39 patients were included in the PROFIP programme. The majority of patients were young male patients with a diagnosis of non‐affective psychosis, and with 56% of patients reporting cannabis use. Patients received pharmacological and psychosocial interventions based on evidence and individual needs. Conclusions Our team allowed young people with early psychosis to receive effective care. We do need improvements, namely in referrals and the education of health professionals. More teams in our country should be constituted, allowing larger numbers of patients with early psychosis to be treated by specialized teams.

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“…Various types of treatment have shown efficacy in these patients. For instance, some authors recommend cognitive behavioural therapy during the acute stage of the disease or during remission [15]. However, systematic reviews have found that integrated treatment (including biological, psychological and social elements) is the approach that most significantly reduces the rates of transition to psychosis and negative symptomatology compared to treatment as usual.…”

Section: Introductionmentioning

confidence: 99%

Integrated treatment of first episode psychosis with online training (e-learning): study protocol for a randomised controlled trial

Barbeito

Vega

Azúa

et al. 2014

Trials

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BackgroundThe integrated treatment of first episode psychosis has been shown to improve functionality and negative symptoms in previous studies. In this paper, we describe a study of integrated treatment (individual psychoeducation complementary to pharmacotherapy) versus treatment as usual, comparing results at baseline with those at 6-month re-assessment (at the end of the study) for these patients, and online training of professionals to provide this complementary treatment, with the following objectives: 1) to compare the efficacy of individual psychoeducation as add-on treatment versus treatment as usual in improving psychotic and mood symptoms; 2) to compare adherence to medication, functioning, insight, social response, quality of life, and brain-derived neurotrophic factor, between both groups; and 3) to analyse the efficacy of online training of psychotherapists.Methods/designThis is a single-blind randomised clinical trial including patients with first episode psychosis from hospitals across Spain, randomly assigned to either a control group with pharmacotherapy and regular sessions with their psychiatrist (treatment as usual) or an intervention group with integrated care including treatment as usual plus a psychoeducational intervention (14 sessions). Training for professionals involved at each participating centre was provided by the coordinating centre (University Hospital of Álava) through video conferences. Patients are evaluated with an extensive battery of tests assessing clinical and sociodemographic characteristics (Positive and Negative Syndrome Scale, State-Trait Anxiety Inventory, Liebowitz Social Anxiety Scale, Hamilton Rating Scale for Depression, Scale to Assess Unawareness of Mental Disorders, Strauss and Carpenter Prognostic Scale, Global Assessment of Functioning Scale, Morisky Green Adherence Scale, Functioning Assessment Short Test, World Health Organization Quality of Life instrument WHOQOL-BREF (an abbreviated version of the WHOQOL-100), and EuroQoL questionnaire), and brain-derived neurotrophic factor levels are measured in peripheral blood at baseline and at 6 months. The statistical analysis, including bivariate analysis, linear and logistic regression models, will be performed using SPSS.DiscussionThis is an innovative study that includes the assessment of an integrated intervention for patients with first episode psychosis provided by professionals who are trained online, potentially making it possible to offer the intervention to more patients.Trial registrationNCT01783457 clinical trials.gov. Date of registration in primary registry 23 January 2013.

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Thérapies cognitives et comportementales après les premiers épisodes psychotiques

Cited by 9 publications

References 21 publications

Mobile App–Based Intervention for Adolescents With First-Episode Psychosis: Study Protocol for a Pilot Randomized Controlled Trial

Mobile App–Based Intervention for Adolescents With First-Episode Psychosis: Study Protocol for a Pilot Randomized Controlled Trial

PROFIP: A Portuguese early intervention programme for first‐episode psychosis in Lisbon

Integrated treatment of first episode psychosis with online training (e-learning): study protocol for a randomised controlled trial

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