Therapeutic success of epidermal grafting in generalized vitiligo is limited by the Koebner phenomenon

Hatchome, Naohiro; Kato, Taizo; Tagami, Hachiro

doi:10.1016/0190-9622(90)70013-8

Cited by 84 publications

(52 citation statements)

References 10 publications

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“…Its clinical relevance is not established; however it seems that Kӧbner may indicate disease activity (Table-2) (Njoo et al, 1999; as cited in Hatchome et al, 1990). Njoo and colleagues have concluded that experimental Kӧbner phenomenon can function as a valuable clinical factor to assess disease activity (Njoo et al, 1999).…”

Section: Role Of Corticosteroids In Treatment Of Vitiligo 209mentioning

confidence: 99%

“…Medical therapies are equally effective in active and stable vitiligo, while surgical procedures are only appropriate for stable one (Njoo et al, 1999;as cited in Falabella et al, 1995;Hatchome et al, 1990). …”

Section: Role Of Corticosteroids In Treatment Of Vitiligo 213mentioning

confidence: 99%

“…Surgical modalities are only appropriate for stable vitiligo (Njoo et al, 1999; as cited in Falabella et al, 1995;Hatchome et al, 1990). They are appropriate for cosmetically sensitive sites such as face and back of hands.…”

Section: Surgical Modalitiesmentioning

confidence: 99%

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Role of Corticosteroids in Treatment of Vitiligo

Bagherani¹

2012

State of the Art of Therapeutic Endocrinology

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Section: Role Of Corticosteroids In Treatment Of Vitiligo 209mentioning

confidence: 99%

Section: Role Of Corticosteroids In Treatment Of Vitiligo 213mentioning

confidence: 99%

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Role of Corticosteroids in Treatment of Vitiligo

Bagherani¹

2012

State of the Art of Therapeutic Endocrinology

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“…If the vitiligo is extensive and only a few patches of pigmented skin remain, skinbleachers such as hydroquinone can be used 57 . Grafting techniques, minigrafts and autologous melanocyte culture have garnered some interest, but these may be limited by the Koebner phenomenon [58][59][60] .…”

Section: Treatmentmentioning

confidence: 99%

“…UVB inhibits fibrinolysis in the upper dermis by the release of PA1. UVA, which penetrates deeper, activates fibrinolysis 60 . In porphyria the stimulus to the dermis is UVA, which is characteristically pigmented but white cells are not attracted.…”

Section: Melasma: a Model Of Incontinencementioning

confidence: 99%

Disorders of Pigmentation of the Skin - Hypotheses Underlying Interventions by Multiple Systems of Medicine:Is there a Role for Integrated Medicine?

Arianayagam

Ryan

2016

Current Science

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Biomedicine has not provided a complete explanation with fully effective therapies for disorders of pigmentation. Biomedicine emphasizes the role of melanocyte for protection from UV rays and as a determinant of skin colour. These important properties acquired a genetic basis much later than other functions, many relating to cell contact as in the keratinocyte -melanocyte unit, or as with the synapses of the neurological system. There are other roles, biochemical and mechanical, of melanocyte. Management that is inclusive of a maximally holistic approach justifies the use of diverse herbals, yoga and concern for cultural awareness provided by integrated medicine. Vitiligo provides a model which demonstrates that Ayurveda has a richer view of its presentations, possibly a stronger line on its pathogenesis, and a huge range of herbals, many now backed by studies from ethnobotanical laboratories, awaiting research into the many possible mechanisms by which they may act in the wide and complex field of melanocyte biochemistry.

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A Systematic Review of Autologous Transplantation Methods in Vitiligo

Njoo¹,

Westerhof²,

Bos³

et al. 1998

Arch Dermatol

163

182

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Objective: A systematic review of the effectiveness, safety, and applicability of autologous transplantation methods in vitiligo. Data Sources: Computerized searches of bibliographical databases, a complementary manual literature search, and contacts with researchers and pharmaceutical firms. Study Selection: Predefined selection criteria were applied to all studies found. Data Extraction: Two investigators independently assessed the articles for inclusion. When there was a disagreement, a third investigator was consulted. Data Synthesis: Sixty-three studies were found, of which 16 reported on minigrafting, 13 on split-thickness grafting, 15 on grafting of epidermal blisters, 17 on grafting of cultured melanocytes, and 2 on grafting of noncultured epidermal suspension. Of these, 39 patient series were included. The highest mean success rates (87%) were

show abstract

Therapeutic success of epidermal grafting in generalized vitiligo is limited by the Koebner phenomenon

Cited by 84 publications

References 10 publications

Role of Corticosteroids in Treatment of Vitiligo

Role of Corticosteroids in Treatment of Vitiligo

Disorders of Pigmentation of the Skin - Hypotheses Underlying Interventions by Multiple Systems of Medicine:Is there a Role for Integrated Medicine?

A Systematic Review of Autologous Transplantation Methods in Vitiligo

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