Therapeutic Response of 70% Trichloroacetic Acid CROSS in Atrophic Acne Scars

Agarwal, Nidheesh; Gupta, Lalit; Khare, Ashok Kumar; Kuldeep, C M; Mittal, Asit

doi:10.1097/dss.0000000000000355

Cited by 29 publications

(37 citation statements)

References 25 publications

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“…The clinical response was graded into: complete response (if there was complete resolution of lesions), partial response (if there was a reduction in the size and/or the total number of warts), and no response (if there was not any change in the size and/or the number of warts) (Moubasher, Hassan, Youssef, & Sabek, ). Side effects during the course of treatment were also recorded. (The verbal rating scale, with prescribed terms such as none, mild, moderate, severe, and unimaginable pain was used to access pain). Patients were asked to grade their satisfaction with the therapy by using a quartile grading system (0 unsatisfied, 1 slightly satisfied, 2 satisfied, or 3 very satisfied) (Agarwal & Gupta, ).…”

Section: Methodsmentioning

confidence: 99%

Intralesional injection of measles, mumps, and rubella vaccine versus cryotherapy in treatment of warts: A randomized controlled trial

El‐Magiud

El‐Samea

Gaber

2020

Dermatologic Therapy

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Cutaneous warts are benign hyperkeratotic papillomas resulting from infection by human papillomavirus (HPV). Cryotherapy is a known method for warts treatment. Immunotherapy stimulates HPV recognition by the immune system; this helps resolution of warts. To determine the efficacy of intralesional immunotherapy with measles, mumps, and rubella (MMR) vaccine versus cryotherapy in the treatment of patients with multiple common and plantar warts. Forty‐eight patients with multiple common and plantar warts were divided into two groups: to undergo either intralesional injection of MMR vaccine (Group A), or cryotherapy (Group B). Forty patients completed the study. In the MMR group, 70% of the patients showed complete response, 5% partial response, and 25% showed no response to treatment. In the CRYO group, 45% of the patients showed complete response, 35% partial response, and 20% showed no response to treatment. The complete response was higher in the MMR group (70%) as compared to the CRYO group (45%), but the difference between the two groups was not statistically significant. Meanwhile, the partial response was significantly higher in the CRYO group. Intralesional MMR injection was a safe and effective treatment for multiple common and plantar warts as compared to cryotherapy.

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Section: Methodsmentioning

confidence: 99%

Intralesional injection of measles, mumps, and rubella vaccine versus cryotherapy in treatment of warts: A randomized controlled trial

El‐Magiud

El‐Samea

Gaber

2020

Dermatologic Therapy

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show abstract

“…9,22 Of note, some studies included a total of 5 patients who were on isotretinoin for 3 or 6 months prior to CROSS method. 9,15 Both studies reported good results without resulting in keloid or hypertrophic scarring. One of these patients experienced prolonged, adherent crusting which persisted for about two weeks.…”

Section: Precare Instructionsmentioning

confidence: 99%

“…The patients were predominantly female except in three studies. [13][14][15] Patients ranged from age 9 to 52. The majority of the studies looked at patients with Fitzpatrick skin phototypes (FST) III-V. Four studies included FST II, 14,[16][17][18] and one study included FST I.…”

Section: Demographics and Clinical Indicationsmentioning

confidence: 99%

“…An ointment or cream-based antibiotic is typically applied after the procedure until crust formation, while one study used emollients without antibiotics. 20 After crusts are detached, some studies instructed patients to use hydroquinone 2%-4% cream, 9,15,19,25 tretinoin cream, 9,25,26 and 20% azelaic acid. 27 All studies emphasized the importance of strict photoprotection after the procedure.…”

Section: Postcare Instructionsmentioning

confidence: 99%

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Chemical reconstruction of skin scars (CROSS) method for atrophic scars: A comprehensive review

Chung

Janahi

Cho³

et al. 2020

J of Cosmetic Dermatology

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Atrophic scarring is a common cosmetic problem in patients seeking dermatologic care. Atrophic scarring can be a sequelae of multiple different disease conditions. 1 Common causes include inflammatory skin conditions, like acne vulgaris, cysts, and discoid lupus erythematosus, and infectious processes, like varicella as well as trauma, burns, and surgery. 1 Postacne scarring occurs in up to 95% of acne patients and is one of the most well-reported and well-studied causes of atrophic scarring. 1,2 Atrophic scarring presents with depressions and uneven texture on the skin surface due to abnormal healing processes, including inadequate collagen and

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“…Approximately a third patients with darker skin type may develop PIH, which may persist in some patients. [ 17 18 ] Better results are observed with 100% compared to 65% TCA CROSS. [ 19 ] Phenol (88%) has been used in place of TCA (90%) with comparable results in V and VI skin type.…”

Section: Hemical R Econstruction Of mentioning

confidence: 99%

Evidence-based surgical management of post-acne scarring in skin of color

Gupta¹,

Kaur

Patra

et al. 2020

J Cutan Aesthet Surg

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Therapeutic Response of 70% Trichloroacetic Acid CROSS in Atrophic Acne Scars

Abstract: The study showed that 70% of TCA is a safe and effective treatment option in all types of atrophic acne scars, especially in severe boxcar scars.

Cited by 29 publications

References 25 publications

Intralesional injection of measles, mumps, and rubella vaccine versus cryotherapy in treatment of warts: A randomized controlled trial

Intralesional injection of measles, mumps, and rubella vaccine versus cryotherapy in treatment of warts: A randomized controlled trial

Chemical reconstruction of skin scars (CROSS) method for atrophic scars: A comprehensive review

Evidence-based surgical management of post-acne scarring in skin of color

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