Therapeutic effects of the levonorgestrel-releasing intrauterine system in the treatment of idiopathic menorrhagia

Xiao, Biao; Wu, Shangchun; Chong, Ju Lian; Zeng, Tao; Han, Lihui; Luukkainen, Tapani

doi:10.1016/s0015-0282(02)04913-0

Cited by 78 publications

(32 citation statements)

References 16 publications

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“…Amongst these women, 57% have occasional bleeding and 35% have amenorrhoea [216]. Significant reduction in menstrual blood loss and increase in haemoglobin and serum ferritin levels were shown to sustain for as long as 36 months in women with idiopathic menorrhagia [217]. Further studies are needed to establish the long-term efficacy of LNG-IUS in the reduction of menstrual blood loss.…”

Section: Levonorgestrel-releasing Intrauterine Devicementioning

confidence: 99%

The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization

et al. 2006

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Summary. The gynaecological and obstetric management of women with inherited coagulation disorders requires close collaboration between obstetrician/ gynaecologists and haematologists. Ideally these women should be managed in a joint disciplinary clinic where expertise and facilities are available to provide comprehensive assessment of the bleeding disorder and a combined plan of management. The haematologist should arrange and interpret laboratory tests and make provision for appropriate replacement therapy. These guidelines have been provided for healthcare professionals for information and guidance and it is also intended that they are readily available for women with bleeding disorders.

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Section: Levonorgestrel-releasing Intrauterine Devicementioning

confidence: 99%

The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization

et al. 2006

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“…Similarly at 12 months, a total rise of 16% from preinsertion level was noted (Graph 2). However, Xiao et al 5 observed an increase in mean Hb% levels of 7.24% at 3 months, 8.64% at 6 months and 9.79% at 12 months. In the present study, the level of women satisfaction on subjective assessment increased steadily with time.…”

Section: Discussionmentioning

confidence: 95%

A Study to Analyze the Efficacy of Levonorgestrel Intrauterine System in the Management of Abnormal Uterine Bleeding among Urban Indian Women

Chowdhury¹,

Sanyal²,

Gupta³

et al. 2017

Journal of SAFOMS

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Objective:The study tried to analyze the efficacy of levonorgestrel intrauterine system (LNGIUS) for the treatment of heavy menstrual bleeding in the urban and suburban Indian women. Materials and methods:The present study was conducted in the Department of Gynecology and Obstetrics, Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan, Kolkata, over a period of 1 year. A total of 20 patients suffering from abnormal uterine bleeding in the age group of 20 to 45 years were recruited in this study. The LNGIUS was inserted in all the women and they were followed up at the end of 3, 6, and 12 months. All subjects completed 1 year duration of follow-up. We used the Student's paired t-test to evaluate the reduction in the menstrual blood loss, passage of clots, and increase in hemoglobin concentration at each point from the baseline. Results:At the end of 6 months, most (90%) of the women had an acceptable bleeding, with 10% having amenorrhea (pictorial blood-loss assessment chart score 0). Statistically significant improvement in the hemoglobin level was observed at the end of 3, 6, and 12 months postinsertion. The level of satisfaction increased steadily with time. Conclusion:Levonorgestrel intrauterine system is an effective reversible treatment for menorrhagia. Levonorgestrel intrauterine system can be used as an effective alternative to hysterectomy in the future in the urban and suburban affluent Indian women.

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“…Reduction in the menstrual bleeding loss and rise in hemoglobin and serum ferritin levels while treating heavy menstrual bleeding is particularly relevant in developing countries. 25 Global evidence has shown that, in addition to long term reduction in menstrual blood loss, LNG IUS also results in increase in hemoglobin levels. 25,26 Similar results have been seen in Indian studies.…”

Section: Indian Evidence Of Lng-iusmentioning

confidence: 99%

“…25 Global evidence has shown that, in addition to long term reduction in menstrual blood loss, LNG IUS also results in increase in hemoglobin levels. 25,26 Similar results have been seen in Indian studies. LNG-IUS has shown to raise hemoglobin level from 5.5-22% over one year period in Indian patients (Figure 2).…”

Section: Indian Evidence Of Lng-iusmentioning

confidence: 99%

Levonorgestrel intrauterine system: A first line medical therapy for idiopathic heavy menstrual bleeding

Mahapatra¹,

Kapur²,

Baxi³

et al. 2015

Int J Reprod Contracept Obstet Gynecol

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Therapeutic effects of the levonorgestrel-releasing intrauterine system in the treatment of idiopathic menorrhagia

Cited by 78 publications

References 16 publications

The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization

The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization

A Study to Analyze the Efficacy of Levonorgestrel Intrauterine System in the Management of Abnormal Uterine Bleeding among Urban Indian Women

Levonorgestrel intrauterine system: A first line medical therapy for idiopathic heavy menstrual bleeding

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