Therapeutic effects of saffron and its components on neurodegenerative diseases

Hamedani, Sahar Golpour-; Pourmasoumi, Makan; Zarifi, Sudiyeh Hejri; Askari, Gholamreza; Jamialahmadi, Tannaz; Bagherniya, Mohammad; Sahebkar, Amirhossein

doi:10.1016/j.heliyon.2024.e24334

Heliyon

2024

DOI: 10.1016/j.heliyon.2024.e24334

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Therapeutic effects of saffron and its components on neurodegenerative diseases

Sahar Golpour- Hamedani,

Makan Pourmasoumi,

Sudiyeh Hejri Zarifi

et al.

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2024

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Cited by 1 publication

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Saffron (Crocus sativus L.) and Its By-Products: Healthy Effects in Internal Medicine

Marrone,

Urciuoli,

Di Lauro

et al. 2024

Nutrients

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Crocus sativus L., commonly known as saffron, is a precious spice coming from Asia, in particular from Iran, the country leader in its production. The spice is derived exclusively from dried stigmas and it is the most expensive one in the world. The areas of application of saffron are multiple, in fact ranging across the food, drinks, pharmaceuticals and cosmetics sectors. As is the case with other phytochemicals, not only the final product but also saffron by-products are considered a valuable source of bioactive natural compounds. In fact, its healthy effects, especially as antioxidants and anti-inflammatories (via reducing pro-inflammatory cytokines), are well-recognized in internal medicine. In particular, its healthy effects are related to counteracting degenerative maculopathy, depression and anxiety, neurodegenerative diseases, metabolic syndrome, cancer and chronic kidney disease, by promoting glucose metabolism. In this review, we summarize the most important papers in which saffron has turned out to be a valuable ally in the prevention and treatment of these pathologies. Moreover, we would like to promote the use of saffron by-products as part of a bio-circular economy system, aimed at reducing wastes, at maximizing the use of resources and at promoting environmental and economic sustainability.

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Saffron (Crocus sativus L.) and Its By-Products: Healthy Effects in Internal Medicine

Marrone,

Urciuoli,

Di Lauro

et al. 2024

Nutrients

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show abstract

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Therapeutic effects of saffron and its components on neurodegenerative diseases

Cited by 1 publication

References 108 publications

Saffron (Crocus sativus L.) and Its By-Products: Healthy Effects in Internal Medicine

Saffron (Crocus sativus L.) and Its By-Products: Healthy Effects in Internal Medicine

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