“…Armentano et al [1936] were the first to report that they had isolated a biologically active substance from lemon juice, and this they named citrin. It has been found in experiments on both human patients [Armentano et al, 1936;Jersild, 1938;Kugelmass, 1940;K aether and Slany, 1940;Vacek, 1941;Scarborough, 1945;HAmori, 1947] and experimental animals [Rusznyak and Benko, 1941] that citrin increases and normalizes pathologically reduced capillary resistance.…”