TheraCal LC: From Biochemical and Bioactive Properties to Clinical Applications

Abstract

Background Direct pulp capping is a popular treatment modality among dentists. TheraCal LC is a calcium silicate-based material that is designed as a direct/indirect pulp capping material. The material might be very attractive for clinicians because of its ease of handling. Unlike other calcium silicate-based materials, TheraCal LC is resin-based and does not require any conditioning of the dentine surface. The material can be bonded with different types of adhesives directly after application. There has been considerable research performed on this material since its launching; however, there are no review articles that collates information and data obtained from these studies. This review discusses the various characteristics of the material with the aim of establishing a better understanding for its clinical use. Methods A search was conducted using search engines (PubMed and Cochrane databases) in addition to reference mining of the articles that was used to locate other papers. The process of searching for the relevant studies was performed using the keywords pulp protection, pulp capping, TheraCal, and calcium silicates. Only articles in English published in peer-reviewed journals were included in the review. Conclusion This review underlines the fact that further in vitro and in vivo studies are required before TheraCal LC can be used as a direct pulp capping material.

Time-Dependent Response of Human Deciduous Tooth-Derived Dental Pulp Cells Treated with TheraCal LC: Functional Analysis of Gene Interactions Compared to MTA

“…Evidence indicated that some resin monomers incorporated in TC may not be polymerized during light curing, and they can be released and pose a detrimental effect on pulp cells [29]. Therefore, it is recommended that TC be placed in thin layers and adequately light cured in 1 mm increments [57].…”

WITHDRAWN: Alkalizing properties of new calcium-silicate endodontic biomaterials

“…The indications and clinical applications for calcium silicatebased cements are pulp capping, pulpotomy, apexogenesis, apexification, perforation and resorption repair, root canal sealers and retograde surgical filling/root-end sealing [1][2][3][4][5][6][7][8][9][10]. Calcium silicate-based materials possess bio-properties like biocompatibility, biointeractivity (release calcium (Ca 2+ ) and hydroxyl (OH -) ions) and bioactivity (apatite-forming ability in contact with body fluids) [1,2,11].…”

“…TheraCal LC (Bisco Inc. Schamburg, IL, USA) is a new light-cured, resin-modified calcium silicate cement, and classified as a 4th generation of calcium silicate material (hybrid CSC) [7]. The manufacturer recommends using TheraCal LC as direct and indirect pulp capping material with an ability to stimulate apatite-like precipitates and dentinal bridge, and as a restorative liner and base [4,7,11,19]. It also shows physiochemical bonding to dentin, good sealing abilities, and it is well tolerated by immortalized odontoblast-like cells [19].…”

Evaluation of bond strength of one step and two steps self-etch adhesive agents with two different pulp-capping materials

“…Bonding begins with the contact of material and water. Unlike Biodentine, TheraCal LC does not include water to hydrate the material, and the bonding process depends on the water captured by the environment and its diffusion into the material [17].…”

“…Vezivanje započinje dodirom materijala i vode. Za razliku od BD, Theracal LC ne uključuje vodu za hidrataciju materijala, a proces vezivanja zavisi od vode koju zarobi iz okoline i njene difuzije u materijal [17]. Snaga veze između restorativnih materijala i materijala za direktno i indirektno zatvaranje pulpe takođe je važna za uspeh restauracija.…”