“…9 Wellens and coworkers10 11 suggested that loss of preexcitation after intravenous administration of a class I antiarrhythmic drug occurs, in general, only with accessory pathway with longer (>270 msec) anterograde refractory periods of the accessory pathways, and evidence supporting this viewpoint has been presented with several class 1 antiarrhythmic drugs. [0][1][2][3][4][5][6][7][8][9][10][11][12] This concept was challenged by Fananapazir and colleagues,13 who found that loss of preexcitation after intravenous procainamide was neither sensitive nor specific for predicting preexcited RR interval of less than 250 msec during atrial fibrillation. Boahene et al14 studied the effects of incremental doses of intravenous procainamide and showed that prediction of minimum preexcited RR interval of less than 250 msec was related to the dose of procainamide.…”
“…9 Wellens and coworkers10 11 suggested that loss of preexcitation after intravenous administration of a class I antiarrhythmic drug occurs, in general, only with accessory pathway with longer (>270 msec) anterograde refractory periods of the accessory pathways, and evidence supporting this viewpoint has been presented with several class 1 antiarrhythmic drugs. [0][1][2][3][4][5][6][7][8][9][10][11][12] This concept was challenged by Fananapazir and colleagues,13 who found that loss of preexcitation after intravenous procainamide was neither sensitive nor specific for predicting preexcited RR interval of less than 250 msec during atrial fibrillation. Boahene et al14 studied the effects of incremental doses of intravenous procainamide and showed that prediction of minimum preexcited RR interval of less than 250 msec was related to the dose of procainamide.…”
“…The annual incidence of newly diagnosed cases is 4/100,000/year 6 . Arrhythmia prevalence is variable (4.3–75%) 13 . Of those initially asymptomatic patients at diagnosis, 30% may develop arrhythmias during a 10‐year follow‐up 6 …”
AF with RVR occurred following AVRT induction during EPS in 34% of our WPW patients, typically associated with right-sided AP locations. Time intervals for RVR to degenerate into ventricular fibrillation and lead to SCD are yet to be determined.
“…The above constellation of EKG findings without any arrhythmias is termed as WPW pattern. The prevalence of WPW pattern on surface ECG is about 0.15 to 0.25 % of general population [2,3].…”
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