Unique wall motion abnormalities on stress echocardiogram associated with Wolff–Parkinson–White pattern electrocardiogram: A case report

Septal Dyskinesia and Global Left Ventricular Dysfunction in Pediatric Wolff‐Parkinson‐White Syndrome with Septal Accessory Pathway

“…[1][2][3][4] Abnormalities of interventricular septal motion in WPW syndrome may result in global left ventricular (LV) dysfunction mimicking dilated cardiomyopathy. 4,5 Radiofrequency catheter ablation (RFA) of APs is an established first-line therapy for symptomatic tachycardia in children. However, there is little known about reverse remodeling of ventricular dysfunction after RFA in WPW syndrome.…”

“…Preexcitation through the AP might affect the motion of the ventricular wall and, thus, the extent and location of preexcited myocardium may be important determinants of global ventricular function. Echocardiography has been used to investigate abnormal wall motion in a limited number of studies 1–4 . Abnormalities of interventricular septal motion in WPW syndrome may result in global left ventricular (LV) dysfunction mimicking dilated cardiomyopathy 4,5 …”

Cardiac Resynchronization Therapy by Ablation of Right-Anterolateral Accessory Pathway

“…LV dysfunction with remodeling in patients with preexcitation‐related dyssynchrony occurs rarely 3–8 and was described mainly in pediatric patients, but also in adults 4–6 . This report demonstrates a reversal of LV dyssynchrony, reverse remodeling and normalization of LV function following right anterolateral accessory pathway ablation during long term follow‐up of 4 years.…”

“…Most of the patients with manifest ventricular preexcitation with lesser or neglectible arrhythmic burden exhibit neither LV dilatation nor LV dysfunction: hence ablation therapy in these cases does not have significant impact on hemodynamics or on biomarkers levels 9 . Nevertheless, it should be emphasized, that in some individuals with right sided accessory pathway, ventricular dyssynchrony caused by preexcitation may be the culprit process for the development of LV dysfunction and heart failure 3–8 . In this regard, echocardiography plays an important role, because successful ablation therapy may normalize LV function in these patients.…”

Echocardiographic characteristics of pediatric preexcitation cardiomyopathy

“…Due to the presence of an AP in patients with preexcitation syndrome, the normal ventricular conduction is changed and some ventricular segments are excited in advance 4 . This leads to abnormal LV wall motion.…”