The Vitiligo Impact Patient Scale (VIPs): Development and Validation of a Vitiligo Burden Assessment Tool

Abstract

Vitiligo has a major impact on health-related quality of life (QOL). Although a few vitiligo specific QOL instruments exist, there is no specific vitiligo burden tool. We developed and validated a specific vitiligo burden tool according to skin phototype. In total, 301patients completed 35-item of the Vitiligo Impact Patient scale (VIPs) of who 235 were of skin phototype I to III and 66 of phototype IV to VI. The dimensionality of the items was evaluated using factor analyses with results suggesting 3 factors in fair and dark skinned patients ("Psychological effects on daily life", "Relationships and Sexuality", and "Economic constraints, Care & Management of Disease"). Unidimensionality was confirmed by higher order factor analysis. Cronbach's α were high and intra-dimensional coherences all demonstrated good reliability (α>0.8). The final instrument consists of 29 items (19 items common to all patients, 3 specific to fair skin and 7 to dark skin. The test-retest reliability demonstrated very good reproducibility. Intra Class Correlation of each dimension was >0.90 for each population. External validity was confirmed by the correlation coefficients and Bland and Altman plots of the VIPs-FS and VIPs-DS versus the SF-12, PVC Metra, BISS and DLQI assessment tools.Journal of Investigative Dermatology accepted article preview online, 08 October 2015. doi:10.1038/jid.2015.398.

Systematic Review of Clinimetric Instruments to determine the severity of Non‐segmental Vitiligo

“…We found one observer‐reported instrument based on the processing of digital images: Digital Imaging Analysis System (DIAS) . Two instruments measured the burden of the disease (VIPs and VIS), and three assessed the quality of life (VitiQoL, VIS22 and VLQI). In this update, the validation of a modified version of a previous instrument was identified (VESplus) .…”

Development and validation of a new tool to assess the Burden of Sensitive Skin (BoSS)

“…Individual burden accounts for the broadest aspects of diseaserelated disability, including psychological, physical, social and economic factors, and may help to monitor specific diseases before and after therapy. [29][30][31] \Sensitive skin is often perceived as a cosmetic disorder, whereas it has an unexpected impact on patients' quality of life. 14,24,28 Currently, the psychological consequences of sensitive skin have been poorly studied.…”

“…6 The management of sensitive skin is based on the cautious use of well-tolerated and soothing cosmetics. 30 To the best of our knowledge, the burden of sensitive skin has yet to be evaluated. 2,4,8 Epidemiological studies show that the prevalence varies by country 9 .…”

“…Individual burden accounts for the broadest aspects of diseaserelated disability, including psychological, physical, social and economic factors, and all of these aspects must be integrated in specifically dedicated questionnaires. 30 To the best of our knowledge, the burden of sensitive skin has yet to be evaluated. Therefore, the aim of this study was to design, develop and validate a specific tool to evaluate the burden of sensitive skin.…”

Palmoplantar keratoderma: creating a disease burden questionnaire

“…This wording was further supplemented by the expertise of two dermatologists in charge of patients with PPK and by an expert in designing patient-reported outcomes. [4][5][6] Following these qualitative interviews, 56 items were retained. The questionnaire was then scrutinized to regroup similar themes, thereby limiting redundancy; 24 questions were created.…”