The Variations in the Altitudes Between the Sea Level and Ajloun Impact Heart Variables, but not Angiotensin Ii

Abstract

Background: hypertension affects many people worldwide and it is highly prevalent in Jordan. Living at different areas with different attitudes may have impacts in hypertension. Study objectives: to identify the prevalence of hypertension in two areas in Jordan with different attitudes and to determine the impact of attitudes in hypertension and angiotensin II to be able to determine the appropriate antihypertensive drug for such population. Methodology: a cross-sectional study design was conducted to collect data from participants. The study included 1000 participants, 500 from each area. A constructed questionnaire was used in this study. Blood samples were taken from participants to assay for angiotensin II. Blood pressure was measured for all patients. Data was analyzed using SPSS version 20. Data was presented as means, frequencies, percentages. The relationship between variables was examined using independent T-test. Significance was considered at alpha level <0.05. European Scientific Journal December 2016 edition vol.12, No.36 ISSN: 1857 -7881 (Print) e -ISSN 1857 447 Study findings: the main findings of the present study were that cardiac variables including SPS, DBP, MBP, and pulse were significantly higher in Ajloun compared with the Sea level area (p=0.001). This is also applied for PCV. The mean concentration of angiotensin II in the Sea level was 11.21± 6.05 pg/ml, and this was lower than that in the Ajloun area 12.08± 5.19, but this mean difference was not statistically significant (p>0.05). Conclusions: living in high altitude is associated with increased potential to have increased levels of cardiac parameters independently of the level of angiotensin II and the therapeutic options for patients with hypertension should be taken into account.