The Vaporization Enthalpy and Vapor Pressure of (d)-Amphetamine and of Several Primary Amines Used as Standards at T/K = 298 As Evaluated by Correlation Gas Chromatography and Transpiration

Abstract

Rostock. The products were analyzed on a Hewlett Packard gas chromatograph 5890Series II equipped with a flame ionization detector and Hewlett Packard 3390A integrator. The dimensions of the capillary column HP-5 (stationary phase crosslinked 5% PH ME silicone) were the following: the column length, inside diameter, and film thickness were 25 m, 0.32 mm and 0.25 µm, respectively. The flow rate of a carrier gas (nitrogen) was 12.1 cm 3 •s -1 . The starting point for the GC temperature program was T/K 323 K with a heating rate of 0.167 K•s -1 up until reaching T/K = 523 K. St.Louis. An HP 5890 gas chromatograph interfaced to a computer running HP Chemstation was used to measure the retention times of all analytes. Helium was the carrier gas and the column used was a 0.32 mm ID, 30 m DB5 column. Experimental retention times are provided below. Isothermal chromatograms of both the target and reference compounds were obtained over a T/K = 30 temperature range at intervals of T/K = 5. The solvents used were not retained on the column at the temperatures of the experiments.Vapour pressure measurements of alkaneamines. Vapour pressures of alkaneamines were determined using the method of transpiration [11, 12] in a saturated nitrogen stream. About 0.5 g of the sample was mixed with glass beads and placed in a thermostatted Ushaped tube having a length of 20 cm and a diameter of 0.5 cm. Glass beads with a diameter of the glass spheres of 1 mm, wash with 0.1M NaOH and dried, provided surface area large enough for rapid vapour-liquid equilibration. At constant temperature

Thermodynamic Properties of Biogenic Amines and Their Solutions

“…Vapor pressures for undecyldiethylamine have been measured for the first time (from 0.77 Pa at 301.2 K up to 99 Pa at 363.2 K). Vapor pressures of benzylamine and phenethylamine were measured in our previous works , by the transpiration method. In this work, we recalculated the published data taking into account not only the n N 2 moles of the carrier gas but also n i moles of compound vapor under study (see eqs and ).…”

“…They will be discussed in the PC-SAFT Modeling of Amine Pure-Component Properties section. Vapor pressures for benzylamine and phenethylamine earlier reported in the literature − are in good agreement as it can be seen in Figures S2 and S3 in the Supporting Information. As far as we know, vapor pressures for phenylethanolamine and halostachine have been measured for the first time in this work.…”

“… a Standard uncertainties are u ( p LV /Pa) = 0.005 + 0.025 ( p LV /Pa) and u ( T ) = 0.1 K. b Recalculated values from ref . …”

Evaluation of the Vaporization Enthalpies and Liquid Vapor Pressures of (R)-Deprenyl, (S)-Benzphetamine, Alverine, and a Series of Aliphatic Tertiary Amines by Correlation Gas Chromatography at T/K = 298.15

“…Reliable vapor pressures of the targets can be obtained using the linear relationship observed between plots of ln­( t 0 / t a ) and ln­( p / p 0 ) of the standards and the ln­( t 0 / t a ) values of the targets to evaluate the vapor pressures of the latter. This correlation repeated as a function of temperature can provide a vapor pressure–temperature profile of the targets. ,,,,, …”

“…( S )-Benzphetamine is a schedule III controlled substance. The vaporization enthalpies and vapor pressures of both amphetamine and ( S )-methamphetamine as evaluated by correlation gas chromatography have recently been reported. , Alverine is a smooth muscle relaxant. It is used in management of disorders of the GI tract and other organs associated with involuntary muscle spasms .…”