The value of preoperative lytic therapy in limb-threatening acute ischemia from popliteal artery aneurysm

Nationwide study of the outcome of popliteal artery aneurysms treated surgically

“…If possible, emergency operation should be avoided and the run‐off be improved by preoperative thrombolysis. Previous investigators have reported good results from thrombolysis of PA, but in small series34–36. In this study run‐off was improved dramatically in most of the 100 treated legs.…”

Outcomes of surgical management for popliteal artery aneurysms: An analysis of 583 cases

“…Overall, in patients with PAA, limbthreatening ischemia has been documented to occur in 17-46% and rupture in 3%. 6,8,[16][17][18][19][20][21] Limb loss from complications of PAA has been observed in as high as 67%. 7,[22][23][24][25] Some have suggested reserving operation for only those with symptoms who were deemed appropriate surgical candidates.…”

Effect of Duplex Arteriography in the Management of Acute Limb-Threatening Ischemia From Thrombosed Popliteal Aneurysms

“…8 Others have suggested that thrombosis of PAA, as the cause of acute limb-threatening ischemia, was underdiagnosed prior to the thrombolytic era. 10,15 On the basis of these data, several authors reported excellent limb salvage by a combination of thrombolytic therapy followed by revascularization 10,8,14 compared with the high amputation rates of surgery alone 2,3 for acute limb-threatening ischemia following thrombosis of PAA. However, preoperative thrombolytic therapy may not be an option in patients presenting with advanced ischemia after thrombosis of PAA or with contraindications to lytic therapy.…”