The value of P300 event related potentials in the assessment of cognitive function in subclinical hypothyroidism

Dejanović, Mirjana; Ivetic, Vesna; Nestorović, Vojkan; Milanovic, Zvezdan; Erić, Mirela

doi:10.23736/s0391-1977.16.02327-0

Cited by 6 publications

(2 citation statements)

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“…ERP technology can reflect the neuroelectrophysiological changes in the brain during the cognitive process and is widely used in studies on neuropsychiatric disorders. ERP P300 is an endogenous cognitive component that is related to advanced psychological activities, such as attention, memory, feeling, learning and reasoning and its latent period and amplitude can reflect the level of cognitive function in different aspects [ 44 ]. Furthermore, we select the N-back task as the evaluation tool of the specific cognitive domain (working memory).…”

Section: Discussionmentioning

confidence: 99%

Effect of 12-week shen-based qigong exercise on the residual symptoms of schizophrenia: Study protocol for a single-centre randomised controlled trial

Lian,

Fan,

Wang

et al. 2023

Contemporary Clinical Trials Communications

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Section: Discussionmentioning

confidence: 99%

Effect of 12-week shen-based qigong exercise on the residual symptoms of schizophrenia: Study protocol for a single-centre randomised controlled trial

Lian,

Fan,

Wang

et al. 2023

Contemporary Clinical Trials Communications

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“…There are studies reporting increase in P3 latency and decrease in its amplitude among adults with hypothyroid and SH [38][39][40][41]. Decreases in amplitude and increases in latency of the P3 component in both clinical and subclinical hypothyroid cases imply that cognitive functions are negatively affected in hypothyroidism including subclinical cases [41].…”

Section: Discussionmentioning

confidence: 99%

Auditory event-related potentials demonstrate early cognitive impairment in children with subclinical hypothyroidism

Atli

Dündar

Bayazit

et al. 2019

Journal of Pediatric Endocrinology and Metabolism

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Background The aim of this study was to examine the cognitive functions of children with subclinical hypothyroidism (SH) and healthy children with the use of auditory event-related potentials (AERPs) and neuropsychological tests. Methods Twenty children aged between 8 and 17 years, diagnosed with SH, and 20 age-matched healthy controls were included in this study. A classical auditory oddball paradigm was applied during the electroencephalography (EEG) recordings, and event-related potentials (ERPs) were evaluated between the 0.5- and 20-Hz frequency intervals. P1, N1, P2, N2 and P3 amplitudes and latencies were measured in Fz, FCz, Cz, CPz, Pz and Oz electrodes. Additionally, a number of neuropsychological tests evaluating the reaction time and various cognitive functions were carried out. Results In children with SH, P3 amplitudes in FCz, Cz and CPz electrodes were significantly lower than those in controls (p < 0.05). In addition to this, the P1N1 and N1P2 peak-to-peak amplitude values were also found to be smaller for children with SH than controls (p < 0.05). With regard to the neuropsychological tests, no significant difference was observed between the SH and control groups on any of the cognitive test parameters, reaction time or correct response rates. Conclusions In the present study, while children with SH did not differ from controls with respect to their cognitive functions evaluated via neuropsychological tests, cognitive differences were detected via electrophysiological investigations. This result implies that implicit changes in cognition which are not yet overtly reflected on neuropsychological tests may be detected at an early stage in children with SH.

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Polymorphisms in the type I deiodinase gene and frontal function in recurrent depressive disorder

Gałecka

Talarowska

Orzechowska

et al. 2016

Advances in Medical Sciences

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The value of P300 event related potentials in the assessment of cognitive function in subclinical hypothyroidism

Cited by 6 publications

References 0 publications

Effect of 12-week shen-based qigong exercise on the residual symptoms of schizophrenia: Study protocol for a single-centre randomised controlled trial

Effect of 12-week shen-based qigong exercise on the residual symptoms of schizophrenia: Study protocol for a single-centre randomised controlled trial

Auditory event-related potentials demonstrate early cognitive impairment in children with subclinical hypothyroidism

Polymorphisms in the type I deiodinase gene and frontal function in recurrent depressive disorder

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