“…Observation may be an option for young women with abnormal cytology, especially those with ASCUS or low-grade SIL. Caution is indicated in applying this option, however, because immediate colposcopy with treatment for all high-grade CIN may remain a useful strategy in clinics like ours, where rates of loss to follow-up can be dramatic [14,15], and the finding of a cytologic abnormality during adolescence may be the only opportunity to intervene in the oncogenic process before women are lost to the medical system.…”