The validity of progesterone level on hCG injection day in the prediction of IVF/ICSI cycles’ outcome

Abstract

The validity of progesterone level on hCG injection day in the prediction of IVF/ICSI cycles' outcome. Clin J Obstet Gynaecol. 2019; 2: 095-100.

Serum Progesterone Level in Agonist and Antagonist Protocols on the Day of Human Chorionic Gonadotropin Triggering in Prediction of Intracytoplasmic Sperm Injection Outcome

“…Another study reported that pregnancy rate in the followed-up cases was 36.7%. A significant negative association was detected between progesterone level at hCG day and the pregnancy outcomes, as serum progesterone has significantly high in non-pregnant compared to pregnant cases (2.26 vs 1.84, p = 0.018) [14] .…”

“…Another study handling the same perspective included a total of 302 cases. Patients were started on antagonist (n=241), short (n=47) or long (n=14) agonist protocols, according to their infertility evaluation [14] . Comparable to the present work, one study included a total of 12 cases and patients were divided according to progesterone level into two equal groups; one with progesterone levels <1.5ng/ml, while the other group had higher levels [15] .…”

“…In contrary to this study, some studies reported that age was not a significant factor between the study cases after classifying them according to progesterone level. Cases with progesterone level < 1.5 ng/ml had a mean age of 32.97 years, while cases with higher levels had a mean of 32.43 years [14] . Endometrial receptivity could rely on the supra-physiological levels of ovarian steroid hormones.…”

“…Abolfotouh et al reported also no significant difference between the study groups regarding the used protocol. The agonist protocol was used in 49.2 and 50.8% of cases in both groups respectively (p = 0.28) [14] . In our study, progesterone level at trigger day was significantly different between the three groups.…”