The utilization of copper/zeolite as catalyst in the microwave-assisted synthesis of some novel sulfonamide derivatives

Abstract

Abstract. Zeolite Y clay modified copper nitrate catalyst was prepared. The obtained catalyst was analyzed by SEM, EDS, and powder XRD techniques. The zeolite Y clay modified copper nitrate catalyst was used for the synthesis of various substituted mesalazine by sulfonylation. The synthesized sulfonamides have been characterized by GC-MS, IR, 1 H, 13C and HSQC NMR techniques. The yield percentages of sulfonamides are more than 85%.

Bio-Potent Sulfonamides

“…Antibacterial activities of all synthesized sulphonamides were evaluated by using standard wellknown Bauer-Kirby disc diffusion method 37 . In this study the authors chosen the Gram-positive bacterial strains such as Micrococcus luteus B. subtilis and Staphylococcus aureus the Gram-negative bacterial strains such as E. coli, P.aeruginosa.…”

“…Antifungal activities of all synthesized mesalazine sulfonamides were determined by using standard wellknown Bauer-Kirby disc diffusion method 37 . The test organisms were subculture using PDA medium.…”

“…Pan et al, 28 synthesized a fewsulfonamides via I 2 -mediated reaction of sodium sulfinates with amines in an aqueous medium at room temperature. Recently Dineshkumar and Thirunarayanan prepared more than 80% yields of mesalazines type sulphonamides 37 . In the literature surey, there is no report available for the ultrasonic assisted fly-ash:H 3 PO 3 nano catalyst 38 catalyzed condensation of substituted benzenesulfonyl chlorides and 4-aminobenzoic acid in ultrasonication under solvent-free conditions and its biological activities.…”

Ultrasound assisted synthesis and spectral correlations of some bio-active E-imines

“…The antibacterial effect of the substituted (E)-N-benzylidene-4-morpholinoanilines is shown in Fig. 4 and the zone of inhibition values [18, 23,24,25,27,[50][51][52][53][54][55][56][57][58][59][60][61] are given Table 9. The corresponding clustered column chart is given in Fig.…”