Cu2+/Zeolite catalyzed aldol condensation: Greener synthesis of 4′-piperidinophenyl enones

Ranganathan, K.; Kamalakkannan, D.; Suresh, R.; Sakthinathan, S.P.; Arulkumaran, R.; Sundararajan, R.; Manikandan, V.; Venkatachalam, P.; Muthuvel, I.; Thirunarayanan, Ganesamoorthy

doi:10.1016/j.matpr.2019.12.120

Cited by 4 publications

(1 citation statement)

References 20 publications

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“…The synthesis of 4-piperidiniphenylenone derivatives was carried out by Ranganathan et al The reaction was performed by a microwave-assisted protocol with solid Cu 2+ /Zeolite catalyst under solvent-free conditions. This approach highlighted that benzaldehydes with electron-donating substituents gave higher yields than those with electron-withdrawing substituents; the best concentration of catalyst was also assessed ( Ranganathan et al, 2020 ).…”

Section: 1 Ultrasound Chemistrymentioning

confidence: 99%

The green chemistry of chalcones: Valuable sources of privileged core structures for drug discovery

Marotta

Rossi²,

Ibba³

et al. 2022

Front. Chem.

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The sustainable use of resources is essential in all production areas, including pharmaceuticals. However, the aspect of sustainability needs to be taken into consideration not only in the production phase, but during the whole medicinal chemistry drug discovery trajectory. The continuous progress in the fields of green chemistry and the use of artificial intelligence are contributing to the speed and effectiveness of a more sustainable drug discovery pipeline. In this light, here we review the most recent sustainable and green synthetic approaches used for the preparation and derivatization of chalcones, an important class of privileged structures and building blocks used for the preparation of new biologically active compounds with a broad spectrum of potential therapeutic applications. The literature here reported has been retrieved from the SciFinder database using the term “chalcone” as a keyword and filtering the results applying the concept: “green chemistry”, and from the Reaxys database using the keywords “chalcone” and “green”. For both databases the time-frame was 2017–2022. References were manually selected based on relevance.

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Section: 1 Ultrasound Chemistrymentioning

confidence: 99%

The green chemistry of chalcones: Valuable sources of privileged core structures for drug discovery

Marotta

Rossi²,

Ibba³

et al. 2022

Front. Chem.

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Catalytic behaviour of solid acidic SO42−-SnO2-fly ash peony flower like nano catalyst on the synthesis of some E-Pyrenyl enones

Sekar

Janaki

Muthuvel

et al. 2021

Materials Today: Proceedings

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Methods and Strategies Used in Green Chemistry: A Review

Sharma

Wakode

Supriya

et al. 2020

COC

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: Green chemistry plays an important role in the development of sustainable production systems which involves tremendous research efforts on the design of synthetic and analytical techniques through resource-efficient ways. The improvement in synthetic reaction performances encourages the modern society to minimize energy and reagent consumption and waste generation. Explosion of the chemicals are referred as extremely toxic substances and have been allied with major harmful health effects, though no cure has been established due to lack of curative therapeutic approaches. In view of the facts, green chemistry strategies trigger a new hope in the synthesis of safer biologically active compounds to meet the demands of disease free environment. Here, we highlighted the development of various compounds and greener techniques such as ultrasound-assisted method, microwave-assisted method, green solvent reactions, solvent free reactions, biomolecules and nanoformulations as a new healthy approach.

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Cu2+/Zeolite catalyzed aldol condensation: Greener synthesis of 4′-piperidinophenyl enones

Cited by 4 publications

References 20 publications

The green chemistry of chalcones: Valuable sources of privileged core structures for drug discovery

The green chemistry of chalcones: Valuable sources of privileged core structures for drug discovery

Catalytic behaviour of solid acidic SO42−-SnO2-fly ash peony flower like nano catalyst on the synthesis of some E-Pyrenyl enones

Methods and Strategies Used in Green Chemistry: A Review

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