The utilization of Chronic Otitis Media Questionnaire-12 in chronic otitis media with or without cholesteatoma

Demir, Berat; Şahin, Akın; Binnetoğlu, Adem; Batman, Caglar

doi:10.1007/s00405-020-06030-7

Cited by 5 publications

(4 citation statements)

References 9 publications

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“…To the best of our knowledge, there is no literature reporting the COMQ-12 scoring to assess CPTBCI-related quality of life. Moreover, the median COMQ-12 score of patients with CPTBCI (Mdn = 34) resembles the score of discharging COM without cholesteatoma (M = 33) as reported by Demir et al (2020). For that reason, this trial confirms the significant socioeconomic and healthcare burden of CPTBCI (mainly chronically discharging radical mastoid cavity), comparable to COM (Khalil and Windle-Taylor, 2003).…”

Section: Discussionsupporting

confidence: 73%

“…The treatment is challenging, especially when the established treatment methods are exhausted. Considering that the CPTBCI is a subtype of chronic otitis media (COM), health-related quality of life can be assessed with patient-reported outcome measures, such as the Chronic Otitis Media Questionnaire-12 (COMQ-12) ( Phillips et al, 2014 ; Demir et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

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Autologous Platelet- and Extracellular Vesicle-Rich Plasma Is an Effective Treatment Modality for Chronic Postoperative Temporal Bone Cavity Inflammation: Randomized Controlled Clinical Trial

Vozel

Božič

Jeran

et al. 2021

Front. Bioeng. Biotechnol.

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PurposeTo determine the efficacy of autologous platelet- and extracellular vesicle-rich plasma (PVRP) to treat chronic postoperative temporal bone cavity inflammation (CPTBCI) after exhausting surgical and standard conservative therapies.Materials and MethodsPatients were randomly allocated to treatment with PVRP (PVRP group) or standard conservative methods (control group) in a setting of four once-monthly checkups and subsequent follow-up. The treatment outcome was measured with the Chronic Otitis Media Questionnaire-12 (COMQ-12), CPTBCI focus surface area, and CPTBCI symptom-free time after the fourth checkup.ResultsEleven patients from each group completed the trial; 95% of patients suffered from chronically discharging mastoid cavity (the type of CPTBCI). Within four checkups, the COMQ-12 score decreased statistically significantly in the PVRP group (p < 0.001) but not in the control group (p = 0.339). The CPTBCI foci surface area decreased statistically significantly between the first and second checkups (p < 0.0005) but not between other checkups (p > 0.05) in the PVRP group. No statistically significant differences in CPTBCI foci surface area were detected between checkups in the control group (p = 0.152). Nine patients from the PVRP group and three patients from the control group were CPTBCI symptom-free at the fourth checkup. The median symptom-free time was 9.2 months (95% CI [7.4, 11.9]) in the PVRP group. Cumulatively, 49% of patients in the PVRP group remained CPTBCI symptom-free for 12.7 months after the fourth checkup.ConclusionAutologous PVRP represents a novel additional and successful treatment modality for a chronically discharging radical mastoid cavity when the surgical and standard conservative treatment methods have been exhausted.Trial Numberhttps://clinicaltrials.gov (NCT04281901).

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Section: Discussionsupporting

confidence: 73%

Section: Introductionmentioning

confidence: 99%

Autologous Platelet- and Extracellular Vesicle-Rich Plasma Is an Effective Treatment Modality for Chronic Postoperative Temporal Bone Cavity Inflammation: Randomized Controlled Clinical Trial

Vozel

Božič

Jeran

et al. 2021

Front. Bioeng. Biotechnol.

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“…Berat et al adapted the COMQ-12 into the Turkish language and conducted a study comparing the data collected from 100 healthy and 100 patients suffering from COM [ 8 ]. They unveiled a statistically outweighed difference between the cholesteatoma and without cholesteatoma groups in regarding total scores.…”

Section: Discussionmentioning

confidence: 99%

“…The formulation of the questionnaire was performed by our work team based on other otologic surveys and our own clinical experience [ 6 – 8 ]. Since the study was conducted in Hungary, the primary language was Hungarian, after which, due to the process of validation and international publication, it was later translated into English.…”

Section: Methodsmentioning

confidence: 99%

Quality-of-life outcomes with endoscopic and microscopic type I tympanoplasty—a prospective cohort study

Pap

Kovács

Bölcsföldi

et al. 2023

Eur Arch Otorhinolaryngol

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Purpose Endoscopic type I tympanoplasty was originally introduced in the 1990s and the extensive spread of this practice can be easily observed. The conventional technique performed involves the repair of a tympanic membrane perforation and is defined as microscopic type I tympanoplasty. The aim of this study is the comparison of quality-of-life (QoL) outcomes with endoscopic to that with microscopic type I tympanoplasty. Methods All patients, or in the case of children with the aid of a parent, were asked to complete a novel QoL questionnaire drafted by our study group. The analysis was performed with descriptive statistics—mean, SD and relative frequency—and with a mixed model (generalized least squares fit). A two-sided p value of < 0.05 was regarded as statistically significant. Results A total of 83 patients completed the questionnaire, 38 in the endoscopic group and 45 in the microscopic group. Every question represented a different. A statistically significant result was found in favor of the endoscopic approach regarding average hospitalization rate (p = 0.003) and cosmetic outcomes (p = 0.015). No statistically significant difference was otherwise observed between the groups. Conclusions Based on our prospective cohort study, the QoL outcomes of endoscopic type I tympanoplasty in terms of postoperative pain, headache, nausea, vomiting, dizziness, taste disorder and hearing were comparable to the microscopic type I tympanoplasty. In regard to cosmetics, an increase in desirable results was achieved in the endoscopic group, particularly the average hospitalization rate proved to be statistically significantly lower than in the microscopic group.

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Quality of life after revision mastoidectomy with mastoid obliteration

Pontillo

Ciprelli

Grillo

et al. 2023

Acta Otorrinolaringologica (English Edition)

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The utilization of Chronic Otitis Media Questionnaire-12 in chronic otitis media with or without cholesteatoma

Cited by 5 publications

References 9 publications

Autologous Platelet- and Extracellular Vesicle-Rich Plasma Is an Effective Treatment Modality for Chronic Postoperative Temporal Bone Cavity Inflammation: Randomized Controlled Clinical Trial

Autologous Platelet- and Extracellular Vesicle-Rich Plasma Is an Effective Treatment Modality for Chronic Postoperative Temporal Bone Cavity Inflammation: Randomized Controlled Clinical Trial

Quality-of-life outcomes with endoscopic and microscopic type I tympanoplasty—a prospective cohort study

Quality of life after revision mastoidectomy with mastoid obliteration

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