2013
DOI: 10.1590/abd1806-4841.20131932
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The use of the Er:YAG 2940nm laser associated with amorolfine lacquer in the treatment of onychomycosis

Abstract: Onychomycosis is a common disease, accounting for up to 50% of all ungual pathologies. We have been developing a clinical trial (ClinicalTrials.gov: NCT01528813) using a 2940nm Er:YAG laser to fractionally ablate human nails in vivo, aiming to increase topical amorolfine lacquer delivery to the nail unit, increasing the efficacy of topical treatment of distal and lateral subungual onychomycosis. Partial results have shown an increase in areas of nail plate free of disease. We believe that ablative lasers can i… Show more

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Cited by 29 publications
(22 citation statements)
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“…Diode lasers operate at temperatures that are safe for human tissues, and ablative lasers include carbon dioxide and erbium lasers, and have also been used [ 67 ]. Combining laser treatment with a specific antifungal treatment, such as topical amorolfine, may also prove an effective strategy [ 86 , 87 ], but more data are needed.…”
Section: Fungal Infections Of the Skinmentioning
confidence: 99%
“…Diode lasers operate at temperatures that are safe for human tissues, and ablative lasers include carbon dioxide and erbium lasers, and have also been used [ 67 ]. Combining laser treatment with a specific antifungal treatment, such as topical amorolfine, may also prove an effective strategy [ 86 , 87 ], but more data are needed.…”
Section: Fungal Infections Of the Skinmentioning
confidence: 99%
“…In addition, the high concentration of energy released by means of this technique allows deeper penetration into the nail plate, eradicating all fungal residues. 2 , 3 , 9 , 12 …”
Section: Discussionmentioning
confidence: 99%
“… 8 In this context, some non conventional treatments for onychomycosis, like laser and photodynamic therapy, have shown effectiveness in combating this infection. 2 , 3 , 4 , 9 , 10 , 11 …”
Section: Introductionmentioning
confidence: 99%
“…Er:YAG 2940 nm) może poprawić efekty uzyskane w wyniku miejscowej farmakoterapii. Dobrą skuteczność takiego połączenia stwierdzono w przypadku amorolfiny stosowanej w postaci lakieru do paznokci [36]. Interesujące jest badanie Lim i wsp.…”
Section: Promieniowanie Laserowe W Leczeniu Grzybicy Paznokciunclassified